M. C. Dugan

Publications8
h-index6
Citations312
Highly Influential Citations12
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Multisite analytic performance studies of a real-time polymerase chain reaction assay for the detection of BRAF V600E mutations in formalin-fixed, paraffin-embedded tissue specimens of malignant…
CONTEXT A polymerase chain reaction-based companion diagnostic (cobas 4800 BRAF V600 Mutation Test) was recently approved by the US Food and Drug Administration to select patients with BRAF-mutant… Expand
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Clinicopathologic Analysis of Pancreatic Adenocarcinoma in African Americans and Caucasians
Introduction African Americans have a higher incidence of pancreatic adenocarcinoma than do Caucasians for unknown reasons. Whether other clinicopathologic differences exist between these two groups… Expand
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Establishment of a human pancreatic tumor xenograft model: potential application for preclinical evaluation of novel therapeutic agents.
Adenocarcinoma of the pancreas is currently the fifth leading cause of death in the United States. It remains generally incurable by available treatment modalities. We report here on the… Expand
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Relationship of family cancer history to the expression of P53, P21WAF-1, HER-2/neu, and K-ras mutation in pancreatic adenocarcinoma
SummaryConclusionIn our series of 81 cases, a history of family cancer was present in 52% of patients (42/81) with pancreatic cancer. Nine percent (7/81) had a family history of pancreatic cancer.… Expand
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Current Concepts in Pancreatic Cancer: Symposium Summary
This recent symposium featured speakers from several clinical and research disciplines. Among the findings: peptic ulcer disease is a significant predisposing risk factor (odds ratio = 3.9) for… Expand
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Automated Area Calculation of Histopathologic Features Using SIVQ
TLDR
We present an evolved area calculation tool, using a high-throughput pattern recognition image analysis algorithm, Spatially Invariant Vector Quantization (SIVQ), which addresses the limitations described above. Expand
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Primary adrenal leiomyosarcoma in acquired immunodeficiency syndrome.
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