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Comprehensive molecular characterization of gastric adenocarcinoma
Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Here we describe a… Expand
Meta-analysis shows that prevalence of Epstein-Barr virus-positive gastric cancer differs based on sex and anatomic location.
BACKGROUND & AIMS Epstein-Barr virus (EBV) has been causally associated with cancer; some gastric carcinomas have a monoclonal EBV genome in every cancer cell, indicating that they arose from a… Expand
Long term follow up of patients treated for Helicobacter pylori infection
Background:Helicobacter pylori infection induces progressive inflammatory changes in the gastric mucosa that may lead to gastric cancer. Understanding long term effects resulting from the cure of… Expand
Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancers
Gastric cancer (GC) is a deadly disease with limited treatment options. Recent studies with PD-1 inhibition have shown promising results in GC, but key questions remain regarding which GC subclass… Expand
The Problem of Helicobacter pylori Resistance to Antibiotics: A Systematic Review in Latin America
- M. C. Camargo, Apolinaria García, +6 authors C. Rabkin
- The American Journal of Gastroenterology
- 1 April 2014
OBJECTIVES:Latin America has a high prevalence of Helicobacter pylori infection and associated diseases, including gastric cancer. Antibiotic therapy can eradicate the bacterial infection and… Expand
Improved survival of gastric cancer with tumour Epstein–Barr virus positivity: an international pooled analysis
Background and objective About 9% of gastric carcinomas have Epstein–Barr virus (EBV) in the tumour cells, but it is unclear whether viral presence influences clinical progression. We therefore… Expand
CagA C-terminal variations in Helicobacter pylori strains from Colombian patients with gastric precancerous lesions.
- L. Sicinschi, P. Correa, +9 authors B. Schneider
- Biology, Medicine
- Clinical microbiology and infection : the…
- 1 April 2010
The C-terminus of the Helicobacter pylori CagA protein is polymorphic, bearing different EPIYA sequences (EPIYA-A, B, C or D), and one or more CagA multimerization (CM) motifs. The number of EPIYA-C… Expand
Risk factors for gastric cancer in Latin America: a meta-analysis
- Patricia Bonequi, F. Meneses-González, P. Correa, C. Rabkin, M. C. Camargo
- Cancer Causes & Control
- 1 February 2013
BackgroundLatin America has among the highest gastric cancer incidence rates in the world, for reasons that are still unknown. In order to identify region-specific risk factors for gastric cancer, we… Expand
Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis.
- M. C. Camargo, R. Mera, +7 authors B. Schneider
- Cancer epidemiology, biomarkers & prevention : a…
BACKGROUND Polymorphisms of interleukin-1B (IL1B) and its receptor antagonist (IL1RN) genes have been inconsistently associated with gastric cancer risk. We examined these associations by performing… Expand
Age-specific trends in incidence of noncardia gastric cancer in US adults.
CONTEXT For the last 50 years, overall age-standardized incidence rates for noncardia gastric cancer have steadily declined in most populations. However, overall rates are summary measures that may… Expand