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Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study
BACKGROUND Whether long-term suppression of replication of hepatitis B virus (HBV) has any beneficial effect on regression of advanced liver fibrosis associated with chronic HBV infection remains… Expand
Hepatitis E Virus Epidemiology in Industrialized Countries
- Pilar Clemente-Casares, S. Pina, +4 authors R. Girones
- Biology, Medicine
- Emerging infectious diseases
- 1 April 2003
To determine the prevalence of Hepatitis E virus (HEV) in industrialized nations, we analyzed the excretion of HEV strains by the populations of Spain, France, Greece, Sweden, and the United States.… Expand
HEV identified in serum from humans with acute hepatitis and in sewage of animal origin in Spain.
- S. Piña, M. Butí, M. Cotrina, J. Piella, R. Gironés
- Medicine, Biology
- Journal of hepatology
- 1 November 2000
BACKGROUND/AIMS Hepatitis E virus (HEV) is an enterically transmitted pathogen that appears sporadically in non-endemic countries. We studied HEV as a causal agent of acute hepatitis cases in the… Expand
The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm
The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed,… Expand
A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel
- M. Cornberg, H. Razavi, +30 authors S. Zeuzem
- Liver international : official journal of the…
- 8 June 2011
Background and Aim: Decisions on public health issues are dependent on reliable epidemiological data. A comprehensive review of the literature was used to gather country‐specific data on risk… Expand
Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia.
BACKGROUND/AIMS Previous studies using standard interferon and ribavirin combination therapy suggested that patients infected with HCV-1 and a low pretreatment HCV-RNA level can be treated for 24… Expand
The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.
- A. Fernandez, Cecilia Rosales, +37 authors M. Esteller
- Biology, Medicine
- Genome research
- 22 December 2008
The natural history of cancers associated with virus exposure is intriguing, since only a minority of human tissues infected with these viruses inevitably progress to cancer. However, the molecular… Expand
Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial.
BACKGROUND Treatment options are limited for patients infected by hepatitis C virus (HCV) with advanced liver disease. We assessed the safety and efficacy of ledipasvir, sofosbuvir, and ribavirin in… Expand
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection.
Hepatitis B virus (HBV) infection remains a global public health problem with changing epidemiology due to several factors including vaccination policies and migration. This Clinical Practice… Expand