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Whole-genome analyses resolve early branches in the tree of life of modern birds
To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handleExpand
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Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
The extreme polymorphism in the human leukocyte antigen (HLA) class I region of the human genome is suggested to provide an advantage in pathogen defence mediated by CD8+ T cells. HLA class IExpand
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An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia
Whole-genome data indicate that early modern humans expanded into Australia 62,000 to 75,000 years ago. We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hairExpand
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Ancient human genome sequence of an extinct Palaeo-Eskimo
We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle inExpand
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The Countryside Ideal: Anglo-American Images of Landscape
'God made the country, man made the town.' William Cowper's words, written two centuries ago, underline an idealisation of rural life and landscape which persists to this day. What are the mainExpand
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Diverse Plant and Animal Genetic Records from Holocene and Pleistocene Sediments
Genetic analyses of permafrost and temperate sediments reveal that plant and animal DNA may be preserved for long periods, even in the absence of obvious macrofossils. In Siberia, five permafrostExpand
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The half-life of DNA in bone: measuring decay kinetics in 158 dated fossils
Claims of extreme survival of DNA have emphasized the need for reliable models of DNA degradation through time. By analysing mitochondrial DNA (mtDNA) from 158 radiocarbon-dated bones of the extinctExpand
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The Isolation of Nucleic Acids from Fixed, Paraffin-Embedded Tissues–Which Methods Are Useful When?
Museums and pathology collections around the world represent an archive of genetic material to study populations and diseases. For preservation purposes, a large portion of these collections has beenExpand
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Evolution and transmission of stable CTL escape mutations in HIV infection
Increasing evidence indicates that potent anti-HIV-1 activity is mediated by cytotoxic T lymphocytes (CTLs); however, the effects of this immune pressure on viral transmission and evolution have notExpand
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Ancient bacteria show evidence of DNA repair
Recent claims of cultivable ancient bacteria within sealed environments highlight our limited understanding of the mechanisms behind long-term cell survival. It remains unclear how dormancy, aExpand
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