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- Publications
- Influence
Whole-genome analyses resolve early branches in the tree of life of modern birds
- E. Jarvis, Siavash Mirarab, +102 authors Guo-Jie Zhang
- Medicine, Biology
- Science
- 12 December 2014
To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle… Expand
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
- P. Kiepiela, A. Leslie, +25 authors P. Goulder
- Biology, Medicine
- Nature
- 9 December 2004
The extreme polymorphism in the human leukocyte antigen (HLA) class I region of the human genome is suggested to provide an advantage in pathogen defence mediated by CD8+ T cells. HLA class I… Expand
An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia
- M. Rasmussen, Xiaosen Guo, +55 authors E. Willerslev
- Biology, Medicine
- Science
- 7 October 2011
Whole-genome data indicate that early modern humans expanded into Australia 62,000 to 75,000 years ago. We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair… Expand
Ancient human genome sequence of an extinct Palaeo-Eskimo
- M. Rasmussen, Y. Li, +49 authors E. Willerslev
- Biology, Medicine
- Nature
- 11 February 2010
We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in… Expand
The Countryside Ideal: Anglo-American Images of Landscape
- M. Bunce
- Geography
- 1 August 1994
'God made the country, man made the town.' William Cowper's words, written two centuries ago, underline an idealisation of rural life and landscape which persists to this day. What are the main… Expand
- 282
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Diverse Plant and Animal Genetic Records from Holocene and Pleistocene Sediments
- E. Willerslev, A. Hansen, +7 authors A. Cooper
- Biology, Medicine
- Science
- 2 May 2003
Genetic analyses of permafrost and temperate sediments reveal that plant and animal DNA may be preserved for long periods, even in the absence of obvious macrofossils. In Siberia, five permafrost… Expand
The half-life of DNA in bone: measuring decay kinetics in 158 dated fossils
- M. Allentoft, M. Collins, +11 authors M. Bunce
- Biology, Medicine
- Proceedings of the Royal Society B: Biological…
- 7 December 2012
Claims of extreme survival of DNA have emphasized the need for reliable models of DNA degradation through time. By analysing mitochondrial DNA (mtDNA) from 158 radiocarbon-dated bones of the extinct… Expand
The Isolation of Nucleic Acids from Fixed, Paraffin-Embedded Tissues–Which Methods Are Useful When?
- M. Gilbert, T. Haselkorn, +5 authors M. Worobey
- Biology, Medicine
- PloS one
- 20 June 2007
Museums and pathology collections around the world represent an archive of genetic material to study populations and diseases. For preservation purposes, a large portion of these collections has been… Expand
Evolution and transmission of stable CTL escape mutations in HIV infection
- P. Goulder, C. Brander, +16 authors B. Walker
- Biology, Medicine
- Nature
- 19 July 2001
Increasing evidence indicates that potent anti-HIV-1 activity is mediated by cytotoxic T lymphocytes (CTLs); however, the effects of this immune pressure on viral transmission and evolution have not… Expand
Ancient bacteria show evidence of DNA repair
- S. Johnson, M. Hebsgaard, +11 authors E. Willerslev
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 4 September 2007
Recent claims of cultivable ancient bacteria within sealed environments highlight our limited understanding of the mechanisms behind long-term cell survival. It remains unclear how dormancy, a… Expand