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Gels and liposomes in optimized ocular drug delivery: studies on ciprofloxacin formulations.
Ciprofloxacin (CPFX) containing therapeutic systems were developed using gel- and liposome-based formulations to minimize tear-driven dilution in the conjunctival sac, a long-pursued objective inExpand
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UV light induced photodegradation of liposome encapsulated fluoroquinolones: An MS study
Abstract Fluoroquinolone antibacterial agents are among the drugs most commonly causing phototoxic side effects. The phototoxicity may be originated in formation of reactive oxygen species uponExpand
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Studies on molecular interactions between nalidixic acid and liposomes.
The interaction between nalidixic acid sodium salt (NANa) and liposomes prepared from alpha-L-dipalmitoyl-phosphatidylcholine (DPPC) or from its binary mixture with dioleoyl-phosphatidylcholineExpand
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Molecular interactions in imatinib-DPPC liposomes.
Imatinib (Gleevec) is a novel chemotherapeutic agent against Bcr-Abl protein tyrozine kinase, playing a crucial role in the therapy of chronic myeloid leukemia (CML) and gastrointestinal stromalExpand
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Molecular interactions between DPPC and morphine derivatives: a DSC and EPR study.
The interaction between different morphine derivatives (morphine, codeine, N-methyl-morphine, N-methyl-codeine) and alpha-L-dipalmitoyl phosphatidylcholine (DPPC) liposomes was studied withExpand
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Physicochemical characterization of stealth liposomes encapsulating an organophosphate hydrolyzing enzyme
The present studies were focused on the preparation and characterization of stericaly stabilized liposomes (SLs) encapsulating a recombinant organophosphorus hydrolyzing phosphotriesterase (OPH)Expand
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Molecular dynamics of the cyclic lipodepsipeptides' action on model membranes: effects of syringopeptin22A, syringomycin E, and syringotoxin studied by EPR technique.
Interaction of pore-forming toxins, syringopeptin22A (SP22A), syringomycin E (SRE) and syringotoxin (ST), with model membranes were investigated. Liposomes were prepared from saturated phospholipidsExpand
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Liposomes for Topical Use: A Physico-Chemical Comparison of Vesicles Prepared from Egg or Soy Lecithin
Developments in nanotechnology and in the formulation of liposomal systems provide the opportunity for cosmetic dermatology to design novel delivery systems. Determination of their physico-chemicalExpand
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Ciprofloxacin encapsulation into giant unilamellar vesicles: membrane binding and release.
This study aimed at investigating some respects of binding and interaction between water-soluble drugs and liposomal carrier systems depending on their size and lamellarity. As model substance,Expand
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Fully On-Line Hyphenation of an Experimental OPLC Separation Unit with Diode-Array Detection and Mass-Spectrometry (OPLC-DAD-MS) for Analysis of Xanthine Compounds
The newly developed experimental OPLC separation unit 100 (OSU 100) has been used for fully on-line multiple hyphenation using the one-channel flowing eluent wall (FEW) arrangement at the inlet. OSUExpand
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