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Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imaging.
OBJECTIVE Cytoarchitectonic changes in the anterior cingulate cortex, hippocampus, subiculum, entorhinal cortex, amygdala, mammillary bodies, and septum were reported in a postmortem study of autism.Expand
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Cortical glucose metabolic rate correlates of abstract reasoning and attention studied with positron emission tomography
Abstract Three groups of young, healthy males underwent positron emission tomography of the head, using 18fluoro-2-deoxyglucose as the uptake tracer. During the uptake, one group (n = 8) did anExpand
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Diffusion tensor imaging findings in first-episode and chronic schizophrenia patients.
OBJECTIVE Comparisons of diffusion tensor imaging (DTI) data between first-episode and chronic schizophrenia patients assessed in different studies have led to the suggestion that the decreasedExpand
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Reduced prefrontal and increased subcortical brain functioning assessed using positron emission tomography in predatory and affective murderers.
There appear to be no brain imaging studies investigating which brain mechanisms subserve affective, impulsive violence versus planned, predatory violence. It was hypothesized that affectivelyExpand
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Response inhibition in adolescents diagnosed with attention deficit hyperactivity disorder during childhood: an event-related FMRI study.
OBJECTIVE Frontostriatal neural abnormalities have been implicated in the response inhibition impairments that are characteristic of attention deficit hyperactivity disorder (ADHD). However, reportsExpand
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Laboratory Induced Aggression: A Positron Emission Tomography Study of Aggressive Individuals with Borderline Personality Disorder
BACKGROUND Borderline personality disorder (BPD) is often associated with symptoms of impulsive aggression, which poses a threat to patients themselves and to others. Preclinical studies show thatExpand
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The thalamus and schizophrenia: current status of research
The thalamus provides a nodal link for multiple functional circuits that are impaired in schizophrenia (SZ). Despite inconsistencies in the literature, a meta analysis suggests that the volume of theExpand
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Effect of sertraline on regional metabolic rate in patients with affective disorder
Seventeen patients with major affective disorder completed a 10-week, placebo-controlled, randomized trial of the serotonin reuptake inhibitor sertraline. Patients underwent positron emissionExpand
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Regional and global changes in cerebral diffusion with normal aging.
BACKGROUND AND PURPOSE We used quantitative diffusion MR imaging to investigate the microstructural changes that occur in white matter during normal aging in order to identify regional changes inExpand
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Volumetric analysis and three-dimensional glucose metabolic mapping of the striatum and thalamus in patients with autism spectrum disorders.
OBJECTIVE In patients with autism, behavioral deficits as well as neuroimaging studies of the anterior cingulate cortex suggest ventral rather than dorsal striatal and thalamic abnormalities inExpand
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