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Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP).
To investigate the role of viral expression in individuals infected with human T-cell lymphotropic virus type 1 (HTLV-1), a real-time quantitative reverse transcription-polymerase chain reaction… Expand
The role of Raf kinase inhibitor protein (RKIP) in health and disease.
Raf kinase inhibitor protein (RKIP) is a member of the phosphatidylethanolamine-binding protein (PEBP) family. RKIP plays a pivotal modulatory role in several protein kinase signaling cascades. RKIP… Expand
Moxifloxacin therapy as a risk factor for Clostridium difficile-associated disease during an outbreak: attempts to control a new epidemic strain.
- P. Biller, B. Shank, +5 authors L. McDonald
- Infection control and hospital epidemiology
- 25 January 2007
An outbreak of Clostridium difficile-associated disease (CDAD) caused by the epidemic North American pulsed-field gel electrophoresis type 1 (NAP1) strain began after a formulary change from… Expand
Raf kinase inhibitor protein: a prostate cancer metastasis suppressor gene.
Defining the mechanisms that confer metastatic ability on cancer cells is an important goal towards prevention of metastasis. A gene array screen between a non-metastatic prostate cancer cell and its… Expand
Meta-analysis of contribution of genetic polymorphisms in drug-metabolizing enzymes or transporters to axitinib pharmacokinetics
- M. Brennan, J. Williams, Y. Chen, M. Tortorici, Y. Pithavala, Y. Liu
- Biology, Medicine
- European Journal of Clinical Pharmacology
- 1 May 2012
PurposeAxitinib, an orally administered inhibitor of vascular endothelial growth factor 1, 2 and 3, is primarily metabolized by cytochrome P450 (CYP) 3A4/5 but is also a substrate for CYP1A2,… Expand
The biology of a prostate cancer metastasis suppressor protein: Raf kinase inhibitor protein
Raf kinase inhibitor protein (RKIP) was originally identified as a protein that bound membrane phospholipids and was named phosphatidylethanolamine binding protein‐2 (PEBP‐2). RKIP was than… Expand
Aging and Executive Function Skills: An Examination of a Community-Dwelling Older Adult Population
The purpose of the present study was to employ the Tower of Hanoi task to the study of possible changes in executive function skills in older adults. The study used a quasi-experimental design, with… Expand
Afraid of Being “Witchy With a ‘B’”: A Qualitative Study of How Gender Influences Residents’ Experiences Leading Cardiopulmonary Resuscitation
- C. Kolehmainen, M. Brennan, Amarette Filut, C. Isaac, M. Carnes
- Academic medicine : journal of the Association of…
- 1 September 2014
Purpose Ineffective leadership during cardiopulmonary resuscitation (“code”) can negatively affect a patient’s likelihood of survival. In most teaching hospitals, internal medicine residents lead… Expand
National Surgical Quality Improvement Program Underestimates the Risk Associated With Mild and Moderate Postoperative Acute Kidney Injury
Objectives:In a single-center cohort of surgical patients, we assessed the association between postoperative change in serum creatinine and adverse outcomes and compared the American College of… Expand
Vascular expression of matrix metalloproteinase-13 (collagenase-3) in basal cell carcinoma.
- Y. Hattori, Kamalakar C. Nerusu, +7 authors J. Varani
- Biology, Medicine
- Experimental and molecular pathology
- 1 June 2003
Matrix metalloproteinase-13 (MMP-13; collagenase-3) was detected in the vasculature from 17 of 20 human basal cell carcinomas as assessed by immunohistology immediately after surgery. In contrast,… Expand