M. Brameier

Publications53
h-index27
Citations3,333
Highly Influential Citations255
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A comparison of linear genetic programming and neural networks in medical data mining
TLDR
An efficient algorithm that eliminates intron code and a demetic approach to virtually parallelize the system on a single processor are discussed, which show that GP performs comparably in classification and generalization.
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NucPred - Predicting nuclear localization of proteins
TLDR
NucPred analyzes patterns in eukaryotic protein sequences and predicts if a protein spends at least some time in the nucleus or no time at all, based on regular expression matching and multiple program classifiers induced by genetic programming.
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1 Linear Genetic Programming
A Mitogenomic Phylogeny of Living Primates
TLDR
One major result is a relatively young date for the most recent common ancestor of all living primates which was estimated to 66-69 million years ago, suggesting that the divergence of extant primates started close to the K/T-boundary.
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Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs
TLDR
Novel insights to RNA-induced gene activity adjustments in human cells are introduced by identifying numerous snoRNA-derived molecules with miRNA-like function, including H/ACA box snoRNAs and C/D box sniRNAs, named sno-miRNAs here, which are complementing the increasing number of studies in the field of small RNAs with regulatory functions.
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Nuclear versus mitochondrial DNA: evidence for hybridization in colobine monkeys
TLDR
This study provides the most comprehensive view on colobine evolution to date and emphasizes that analyses of various molecular markers, such as mobile elements and sequence data from multiple loci, are crucial to better understand evolutionary relationships and to trace hybridization events.
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Gibbon genome and the fast karyotype evolution of small apes
TLDR
The assembly and analysis of a northern white-cheeked gibbon genome is presented and the propensity for a gibbon-specific retrotransposon (LAVA) to insert into chromosome segregation genes and alter transcription by providing a premature termination site is described, suggesting a possible molecular mechanism for the genome plasticity of the gibbon lineage.
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On linear genetic programming
TLDR
Typical GP phenomena, such as non-effective code, neutral variations, and code growth are investigated from the perspective of linear GP.
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Explicit Control of Diversity and Effective Variation Distance in Linear Genetic Programming
TLDR
Distance information between individuals is used to control structural diversity of population individuals actively by a two-level tournament selection and variation distance is controlled on the effective code for different genetic operators - including a mutation operator that works closely with the applied distance metric.
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Mitogenomic phylogeny of the common long-tailed macaque (Macaca fascicularis fascicularis)
TLDR
The application of complete mtDNA genomes yields new insights into the evolutionary history of M. f.
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