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Confocal laser scanning microscopy of porcine skin: implications for human wound healing studies
It is concluded that CLSM provides valuable additional morphological information to material examined by conventional microscopy and is useful for wound healing studies in the porcine model.
Microarray-based identification of clinically relevant vaginal bacteria in relation to bacterial vaginosis.
POBASCAM, a population‐based randomized controlled trial for implementation of high‐risk HPV testing in cervical screening: Design, methods and baseline data of 44,102 women
This study indicates that large‐scale hrHPV testing by GP5+/6+ PCR‐EIA in the setting of population‐based cervical screening is practically feasible, is accepted by both participating women and general practitioners and yields highly reproducible results.
Inflammatory events as detected in cervical smears and squamous intraepithelial lesions
- A. Roeters, M. Boon, M. van Haaften, F. Vernooij, T. Bontekoe, A. Heintz
- Biology, MedicineDiagnostic cytopathology
- 30 September 2009
An oversight of HSIL and the full range of cervical infections as detected by cytology, proving that this infectious byproduct of screening can be very valuable.
PCR based high risk HPV testing is superior to neural network based screening for predicting incident CIN III in women with normal cytology and borderline changes.
High risk HPV testing is superior to neural network based screening in identifying women at risk of developing CIN III, and for women with normal cytology and borderline changes and a negative high risk HPV test, the screening interval can be considerably prolonged.
Notes on the application of microwaves for antigen retrieval in paraffin and plastic tissue sections.
Microwave antigen retrieval can also be applied for immunohistochemistry on plastic GMA sections, where the action of the microwave method is probably mainly due to breaking the bonds between GMA and proteins prohibiting immunostaining.
Molecular assessment of bacterial vaginosis by Lactobacillus abundance and species diversity
An affordable and simple molecular test showing a depletion of the genus Lactobacillus in combination with an increased species diversity of vaginal microbiota could serve as an alternative and practical diagnostic method for the assessment of BV.
Microwave‐stimulated diffusion for fast processing of tissue: reduced dehydrating, clearing, and impregnating times
The method is based on microwave‐stimulated diffusion reducing the dehydrating, clearing, and impregnating times by a factor of 48, and the histotechnical microwave results are light‐microscopically excellent and indistinguishable from those of the well‐performed ‘classical’ method.