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A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior
TLDR
An electroencephalographic-derived index of human consciousness that reflects the information content of the brain’s response to a magnetic stimulus is defined, and appears to be a robust measure that distinguishes conscious from unconscious states well enough to be used on an individual basis, a prerequisite for deployment in the clinic. Expand
Integrated information theory: from consciousness to its physical substrate
TLDR
How integrated information theory accounts for several aspects of the relationship between consciousness and the brain is discussed and can be used to develop new tools for assessing consciousness in non-communicative patients. Expand
Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment
TLDR
Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus. Expand
Hemodynamic cerebral correlates of sleep spindles during human non-rapid eye movement sleep
TLDR
The recruitment of partially segregated cortical networks for slow and fast spindles further supports the existence of two spindle types during human non-rapid eye movement sleep, with potentially different functional significance. Expand
Baseline brain activity fluctuations predict somatosensory perception in humans
TLDR
Results indicate a positive relationship between conscious perception of low-intensity somatosensory stimuli and immediately preceding levels of baseline activity in medial thalamus and the lateral frontoparietal network, respectively, which are thought to relate to vigilance and “external monitoring". Expand
Neural correlates of consciousness: progress and problems
Nature Reviews Neuroscience 17, 307–321 (2016) The traces in panel e of Figure 3 were incorrectly colour coded. The colour coding has been corrected in the online version of the article.
Detecting Awareness in the Vegetative State
TLDR
Functional magnetic resonance imaging was used to demonstrate preserved conscious awareness in a patient fulfilling the criteria for a diagnosis of vegetative state and the patient activated predicted cortical areas in a manner indistinguishable from that of healthy volunteers. Expand
Breakdown of within- and between-network Resting State Functional Magnetic Resonance Imaging Connectivity during Propofol-induced Loss of Consciousness
TLDR
It is suggested that propofol-induced unconsciousness could be linked to a breakdown of cerebral temporal architecture that modifies both within- and between-network connectivity and thus prevents communication between low-level sensory and higher-order frontoparietal cortices, thought to be necessary for perception of external stimuli. Expand
Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients.
TLDR
It is shown that default network connectivity is decreased in severely brain-damaged patients, in proportion to their degree of consciousness impairment, as well as in healthy controls and locked-in syndrome patients. Expand
Recovery of cortical effective connectivity and recovery of consciousness in vegetative patients
TLDR
Measurements of effective connectivity by means of transcranial magnetic stimulation combined with electroencephalography can be performed at the bedside while by-passing subcortical afferent and efferent pathways, and without requiring active participation of subjects or language comprehension; hence, they offer an effective way to detect and track recovery of consciousness in brain-injured patients who are unable to exchange information with the external environment. Expand
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