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Tumor necrosis factor increases serum leptin levels in humans.
TLDR
The study shows that leptin serum levels are under control of TNF, a pleiotropic hormone believed to regulate body weight.
Pentraxin 3 is elevated in haemodialysis patients and is associated with cardiovascular disease.
TLDR
The increase in PTX3 production in whole blood after HD indicates that the HD procedure itself contributes to elevatedPTX3 levels in HD patients, and the association between PTX2 and cardiovascular morbidity suggests a possible connection of PTX 3 with atherosclerosis and cardiovascular disease inHD patients.
Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and
TLDR
An important role is suggested of VCAM-1 in atherosclerosis and this work suggests it could be used to indicate stages of atherosclerotic changes with a high degree of statistical significance.
Release of thrombomodulin from endothelial cells by concerted action of TNF-alpha and neutrophils: in vivo and in vitro studies.
TLDR
The concerted action of cytokine-stimulated endothelial cells and neutrophils results in release of TM from cultured endothelial Cells after rhTNF-alpha therapy, which might explain the increased serum TM levels observed in diseases associated with increased systemic or local levels of inflammatory cytokines.
Point and Diffuse Loads of Selected Pollutants in the River Rhein and its Main Tributaries
The research described in this working paper was conducted for the study "Sources of Chemical Pollution in the Rhine Basin," a collaborative effort between IIASA and the Netherlands National
Kinetics of thrombomodulin release and endothelial cell injury by neutrophil‐derived proteases and oxygen radicals
TLDR
In vitro studies confirm in vitro that soluble thrombomodulin is not only a parameter of advanced endothelial cell destruction itself but also in addition an early marker of initial endothelium cell membrane changes induced by neutrophil derived proteases and oxygen radicals.
Proteome scale turnover analysis in live animals using stable isotope metabolic labeling.
TLDR
The ProTurnyzer software is developed that allows the determination of protein fractional synthesis rates without the need of precursor relative isotope abundance information and is applied to mouse brain and plasma proteomes for automated turnover studies.
Serum thrombomodulin—a reliable marker of disease activity in systemic lupus erythematosus (SLE): advantage over established serological parameters to indicate disease activity
TLDR
Soluble thrombomodulin is the most important serological parameter of disease activity in SLE currently available, as shown by the in’vivo studies.
Prevalence of silent gastric ulcer, erosions or severe acute gastritis in patients with type 2 diabetes mellitus--a cross-sectional study.
TLDR
The results of this study indicate that severe acute gastric inflammation or ulcer disease can occur with high prevalence in patients with diabetes mellitus with little or no dyspeptic symptoms.
IRON SUPPLY OF CUCUMBERS IN SUBSTRATE CULTURE WITH HUMATE
The aim of the experiments was to investigate the effect of application of a well soluble Fe-humate (HUMIRON) on rhizosphere and leaves, respectively, on the growth and yield of cucumbers (Cucumis
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