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Mitigating amphibian chytridiomycosis with bioaugmentation: characteristics of effective probiotics and strategies for their selection and use.
TLDR
To target at-risk species and amphibian communities, this work develops sampling strategies and filtering protocols that result in probiotics that inhibit Bd under ecologically relevant conditions and persist on susceptible amphibians.
Antifungal isolates database of amphibian skin-associated bacteria and function against emerging fungal pathogens
TLDR
This work presents a comprehensive Antifungal Isolates Database of amphibian skin-associated bacteria that have been cultured, isolated, and tested for antif fungus properties, and provides empirical data for comparative and bioinformatic studies.
Shifts in disease dynamics in a tropical amphibian assemblage are not due to pathogen attenuation
TLDR
The results suggest that host recoveries are not caused by pathogen attenuation and may be due to shifts in host responses, which provide insights into the mechanisms underlying disease transitions, which are increasingly important to understand in an era of emerging infectious diseases and unprecedented global pandemics.
Amphibian gut microbiota shifts differentially in community structure but converges on habitat-specific predicted functions
TLDR
It is shown that gut and skin microbiota are habitat-specific, demonstrating environmental factors mediate community structure and gut microbiota appears to exhibit metagenomic plasticity.
Composition of the Cutaneous Bacterial Community in Japanese Amphibians: Effects of Captivity, Host Species, and Body Region
TLDR
The cutaneous microbiota of amphibians is confirmed as a highly dynamic system influenced by a complex interplay of numerous factors, revealing an intrinsic host effect.
Widespread presence of the pathogenic fungus Batrachochytrium dendrobatidis in wild amphibian communities in Madagascar
TLDR
Results may suggest that Bd arrived recently, but do not exclude the existence of a previously undetected endemic Bd genotype, which could pose significant threats to Madagascar's unique “megadiverse” amphibians.
Using “Omics” and Integrated Multi-Omics Approaches to Guide Probiotic Selection to Mitigate Chytridiomycosis and Other Emerging Infectious Diseases
TLDR
Using 16S rRNA gene amplicon sequencing and methods such as indicator species analysis, the Kolmogorov–Smirnov Measure, and co-occurrence networks to identify bacteria that are associated with pathogen resistance in field surveys and experimental trials is recommended.
Gut bacterial communities across tadpole ecomorphs in two diverse tropical anuran faunas
TLDR
This study used high-throughput sequencing of partial sequences of the bacterial 16S rRNA gene to assess the diversity of the gut-inhabiting bacterial communities of tropical anuran amphibians from Brazil and Madagascar to suggest a community turnover at metamorphosis.
Cryptic diversity of a widespread global pathogen reveals expanded threats to amphibian conservation
TLDR
This study uses a custom method for genotyping degraded Bd DNA samples, such as those nondestructively collected from live animal or museum specimen skin swabs, and presents the discovery of a divergent lineage of Bd—BdASIA3, that appears to be widespread in Southeast Asia.
Amphibian skin microbiota exhibits temporal variation in community structure but stability of predicted Bd-inhibitory function
TLDR
It is found that the proportion of reads associated with ‘potentially’ Bd-inhibitory OTUs did not vary temporally for two of three newt species, suggesting that protective function may be maintained despite temporal variation in community structure.
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