• Publications
  • Influence
Epidemiology of invasive meningococcal disease in the Netherlands, 1960-2012: an analysis of national surveillance data.
Incidence of invasive meningococcal disease has decreased, but decreasing rates of penicillin susceptibility and the possible resurgence of this devastating disease remain a threat to public health. Expand
Incidence of invasive group B streptococcal disease and pathogen genotype distribution in newborn babies in the Netherlands over 25 years: a nationwide surveillance study.
The introduction of prevention guidelines for invasive group B streptococcus disease in 1999 did not reduce the incidence of disease in neonates, and alternative approaches to prevent infant invasive groupB streptitis disease should be sought. Expand
Listeria monocytogenes sequence type 6 and increased rate of unfavorable outcome in meningitis: epidemiologic cohort study.
The rate of unfavorable outcome among adults with listerial meningitis has increased over a 14-year period, from 27% to 61%. Expand
A decade of herd protection after introduction of meningococcal serogroup C conjugate vaccination.
Herd protection was responsible for >36% of MCC vaccine impact and lasted for ≥10 years and provide further evidence that herd protection results from reduced carriage of virulent meningitis. Expand
The road to tuberculosis treatment in rural Nepal: A qualitative assessment of 26 journeys
Patient routes towards tuberculosis treatment are characterised by self referral and include both private and public health care providers and given the importance of the private practitioners in the patient routes, quality improvement initiatives need to address the public sector but the private health care sector as well. Expand
Community-acquired bacterial meningitis in adults in the Netherlands, 2006-14: a prospective cohort study.
The incidence of adult bacterial meningitis has decreased substantially, which is partly explained by herd protection by paediatric conjugate vaccines. Expand
Listeria monocytogenes meningitis in the Netherlands, 1985–2014: A nationwide surveillance study
The incidence of neonatal listerial meningitis has declined over the past 25 years and the genotype CC6 has become the predominant genotype in L. monocytogenesMeningitis in the Netherlands. Expand
Pyuria is absent during urinary tract infections in neutropenic patients
To investigate the diagnostic significance of a normal urine sediment in the work‐up for fever of unknown origin in neutropenia. Urinary tract infection was defined as ≥105 urinary pathogens in theExpand
Impact of an evidence-based guideline on the management of community-acquired bacterial meningitis: a prospective cohort study.
The guideline introduction was associated with a trend towards early initiation of treatment before imaging and with increased adherence to antibiotic policy and there was no association between delay in antibiotic treatment due to imaging before LP and unfavourable outcome. Expand
Community-acquired group B streptococcal meningitis in adults: 33 cases from prospective cohort studies.
GBS is a rare cause of meningitis in adults that more frequently occurs in patients with underlying comorbidities and GBS serotype V is associated with poor outcome. Expand