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Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.
- J. Vrbíková, M. Bičı́ková, J. Tallová, M. Hill, Ľ. Stárka
- Experimental and clinical endocrinology…
- 27 March 2002
Treatment with metformin in women with PCOS can lead to the increase in homocysteine levels--a risk factor for atherosclerosis. Expand
Selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in normal pressure hydrocephalus.
- L. Sosvorová, J. Vcelak, M. Mohapl, J. Vítků, M. Bičı́ková, R. Hampl
- Neuro endocrinology letters
CSF can better show the neurodegenerative changes in the brain, and the cytokines IL-1β, IL-6 and IL-10 may be helpful in NPH diagnostics. Expand
Determination of steroid metabolome as a possible tool for laboratory diagnosis of schizophrenia
- M. Bičı́ková, M. Hill, D. Řípová, P. Mohr, R. Hampl
- Medicine, Biology
- The Journal of Steroid Biochemistry and Molecular…
- 31 January 2013
The findings suggest that the assessment of steroid levels may become a valid and accurate laboratory test in psychiatry, and steroid metabolome model may be used as a diagnostic tool for further studies. Expand
Associations of bisphenol A and polychlorinated biphenyls with spermatogenesis and steroidogenesis in two biological fluids from men attending an infertility clinic.
The data indicate that BPA influences human gonadal and adrenal steroidogenesis at various steps, and may negatively contribute to the final state of sperm quality. Expand
Serum Concentrations of Some Neuroactive Steroids in Women Suffering from Mixed Anxiety-Depressive Disorder
- M. Bičı́ková, J. Tallová, M. Hill, Z. Krausová, R. Hampl
- Neurochemical Research
- 1 December 2000
The results indicate that imbalance in neuroactive steroids may play a negative role in origin and course of psychiatric and neurological disorders. Expand
Hyperandrogenic states in pregnancy.
There is a significant risk of virilization of the female fetus if the mother's hyperandrogenic state is serious, and this condition most frequently arises in the third trimester. Expand
Differences in bisphenol A and estrogen levels in the plasma and seminal plasma of men with different degrees of infertility.
Overall, a disruption of estrogen metabolism was observed together with a weak but significant impact of BPA on sperm count and concentration, and this point to the importance of seminal plasma in BPA research. Expand
Neuro- and immunomodulatory steroids and other biochemical markers in drug-naive schizophrenia patients and the effect of treatment with atypical antipsychotics.
Lower levels of 7α-hydroxydehydroepiandrosterone, abundant especially in brain, determined for the first time in schizophrenia patients, are in agreement with recent opinion of their neuroprotective and immunoprotective role. Expand
Steroid sulfatase and sulfuryl transferase activity in monkey brain tissue
The results will serve as a basis for further studies concerning the pathophysiology of human brain tumors and steroid sulfatase activity was determined in in vitro microsomal samples from each of the above-mentioned brain regions. Expand
Plasma Thiols and Androgen Levels in Polycystic Ovary Syndrome
- J. Vrbíková, J. Tallová, M. Bičı́ková, K. Dvor̆áková, M. Hill, Ľ. Stárka
- Biology, Medicine
- Clinical chemistry and laboratory medicine
- 21 February 2003
It is concluded that homocysteine is increased in women with polycystic ovary syndrome and is probably linked to androgen levels but not to markers of insulin resistance or with lipid metabolism. Expand