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- Publications
- Influence
Byonic: Advanced Peptide and Protein Identification Software
- M. Bern, Y. J. Kil, C. Becker
- Computer Science, Medicine
- Current protocols in bioinformatics
- 1 December 2012
TLDR
Automatic particle selection: results of a comparative study.
- Y. Zhu, B. Carragher, +14 authors C. S. Potter
- Biology, Medicine
- Journal of structural biology
- 2004
Manual selection of single particles in images acquired using cryo-electron microscopy (cryoEM) will become a significant bottleneck when datasets of a hundred thousand or even a million particles… Expand
Automated N-glycopeptide identification using a combination of single- and tandem-MS.
- David Goldberg, M. Bern, +4 authors A. Dell
- Chemistry, Medicine
- Journal of proteome research
- 30 August 2007
We describe Peptoonist, a program that can automatically identify the glycans (sugars) present at each N-glycosylation site of a protein. The input to Peptoonist is a series of mass spectra, both MS… Expand
Glycoproteomic Analysis of the Secretome of Human Endothelial Cells*
- Xiaoke Yin, M. Bern, Qiuru Xing, Jenny T C Ho, Rosa I Viner, M. Mayr
- Biology, Medicine
- Molecular & Cellular Proteomics
- 23 January 2013
Previous proteomics studies have partially unraveled the complexity of endothelial protein secretion but have not investigated glycosylation, a key modification of secreted and membrane proteins for… Expand
Molecular analyses of dinosaur osteocytes support the presence of endogenous molecules.
- M. Schweitzer, W. Zheng, T. Cleland, M. Bern
- Biology, Medicine
- Bone
- 2013
The discovery of soft, transparent microstructures in dinosaur bone consistent in morphology with osteocytes was controversial. We hypothesize that, if original, these microstructures will have… Expand
A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ
- J. Gajewiak, L. Azam, +16 authors Min-min Zhang
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 4 February 2014
Significance A biochemically unique cone snail venom peptide has been characterized that may be used to probe unexplored but important features of the diverse voltage-gated Na channel isoforms that… Expand
Preview: a program for surveying shotgun proteomics tandem mass spectrometry data.
- Y. J. Kil, C. Becker, W. Sandoval, David Goldberg, M. Bern
- Chemistry, Medicine
- Analytical chemistry
- 13 June 2011
Database search programs for peptide identification by tandem mass spectrometry ask their users to set various parameters, including precursor and fragment mass tolerances, digestion specificity, and… Expand
Elucidating in Vivo Structural Dynamics in Integral Membrane Protein by Hydroxyl Radical Footprinting*
- Y. Zhu, Tiannan Guo, +6 authors S. Sze
- Chemistry, Medicine
- Molecular & Cellular Proteomics
- 26 May 2009
We describe here a novel footprinting technique to probe the in vivo structural dynamics of membrane protein. This method utilized in situ generation of hydroxyl radicals to oxidize and covalently… Expand
Toward Automated N-Glycopeptide Identification in Glycoproteomics.
- Ling Lee, E. S. Moh, B. Parker, M. Bern, N. Packer, M. Thaysen-Andersen
- Biology, Medicine
- Journal of proteome research
- 2 September 2016
Advances in software-driven glycopeptide identification have facilitated N-glycoproteomics studies reporting thousands of intact N-glycopeptides, i.e., N-glycan-conjugated peptides, but the automated… Expand
Extended O-GlcNAc on HLA Class-I-Bound Peptides.
- F. Marino, M. Bern, +6 authors A. Heck
- Chemistry, Medicine
- Journal of the American Chemical Society
- 19 August 2015
We report unexpected mass spectrometric observations of glycosylated human leukocyte antigen (HLA) class I-bound peptides. Complemented by molecular modeling, in vitro enzymatic assays, and oxonium… Expand