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Evaluation and Treatment of Functional Constipation in Infants and Children: Evidence-Based Recommendations From ESPGHAN and NASPGHAN
TLDR
This evidence-based guideline provides recommendations for the evaluation and treatment of children with functional constipation to standardize and improve their quality of care and be used in daily practice and as a basis for further clinical research. Expand
Childhood functional gastrointestinal disorders: neonate/toddler.
TLDR
There has been little or no change for infant regurgitation, infant rumination syndrome, or infant dyschezia, and data-driven changes in diagnostic criteria for functional constipation appear to be less rigid and more inclusive than previous criteria. Expand
Epidemiology of constipation in children and adults: a systematic review.
TLDR
The epidemiology of constipation in children was investigated in 19 articles and prevalence rate was between 0.7% and 29.6% (median 12%). Expand
Epidemiology of Childhood Constipation: A Systematic Review
TLDR
A systematic review of the published literature found that childhood constipation is a common problem worldwide and large epidemiologic studies with the use of generally accepted diagnostic criteria are needed to define the precise prevalence of constipation. Expand
Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease
TLDR
In infant GORD, acid reflux associated TLOSRs are abnormally common and likely to be a major contributing factor to the pathophysiology of GORD. Expand
PEG 3350 (Transipeg) versus lactulose in the treatment of childhood functional constipation: a double blind, randomised, controlled, multicentre trial
TLDR
PEG 3350 patients reported less abdominal pain, straining, and pain at defecation than children using lactulose, and bad taste was reported significantly more often in the PEG group, which should be the laxative of first choice in childhood constipation. Expand
Childhood constipation: longitudinal follow-up beyond puberty.
TLDR
After intensive initial medical and behavioral treatment, 60% of all children referred to a tertiary medical center for chronic constipation were treated successfully at 1 year of follow-up, contradicting the general belief that childhood constipation gradually disappears before or during puberty. Expand
Epidemiology of Pediatric Functional Abdominal Pain Disorders: A Meta-Analysis
TLDR
Functional abdominal pain disorders are a common problem worldwide with irritable bowel syndrome as most encountered abdominal pain-related functional gastrointestinal disorder and is associated with the presence of anxiety and depressive disorders, stress and traumatic life events. Expand
Health utilization and cost impact of childhood constipation in the United States.
TLDR
It is demonstrated that childhood constipation has a significant impact on the use and cost of medical care services, and the estimated cost per year is 3 times than that in children without constipation, which likely is an underestimate of the actual burden of Childhood constipation. Expand
Diagnostic Tests in Hirschsprung Disease: A Systematic Review
TLDR
RSB and ARM are the most accurate tests in the diagnostic workup of Hirschsprung disease. Expand
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