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Immunoglobulin G-dependent enhancement of the infection with Coxsackievirus B4 in a murine system
ABSTRACT It was demonstrated that specific IgG can enhance the infection with CV-B4, in vitro, in the human system. This enhancement could be involved in the pathophysiology of CV-B4 inducedExpand
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Impact of coxsackievirus-B4E2 combined with a single low dose of streptozotocin on pancreas of outbred mice: investigation of viral load, pathology and inflammation
Coxsackieviruses B (CV-B) belong to the EV-B species. CV-B and particularly CV-B4 are thought to be involved in the development of chronic diseases like type 1 diabetes (T1D). The mechanisms of theExpand
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Anti-coxsackievirus B4 (CV-B4) enhancing activity of serum associated with increased viral load and pathology in mice reinfected with CV-B4
ABSTRACT In previous studies it was shown that inoculation of Swiss albino mice with CV-B4 E2 resulted in the production of serum IgG capable of enhancing the CV-B4 E2 infection of murine spleenExpand
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Coxsackievirus-B4E2 can infect monocytes and macrophages in vitro and in vivo.
Viral RNA (vRNA) is found in mice inoculated with coxsackievirus-B4E2 (CV-B4E2). The CV-B4E2 infection of murine spleen cells in vitro is enhanced with CV-B4E2-infected mouse serum. It has beenExpand
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Fluoxetine can inhibit coxsackievirus-B4 E2 in vitro and in vivo.
Group B Coxsackieviruses (CV-B) are responsible for various acute human diseases, and they are involved in chronic diseases such as type 1 diabetes. It has been reported that fluoxetine (FLX)Expand
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Human herpesvirus-6 is present at higher levels in the pancreatic tissues of donors with type 1 diabetes.
Human herpesvirus-6 (HHV-6) is a ubiquitous pathogen associated with nervous and endocrine autoimmune disorders. The aim of this study was to investigate the presence of HHV-6 in pancreatic tissueExpand
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Exposure of Piglets to Enteroviruses Investigated by an Immunoassay Based on the EV-G1 VP4 Peptide
Objective: The aim of this study was to investigate the exposure of piglets to enteroviruses-G (EV-G) through the presence of antibodies in their serum. Methods: Serum samples were obtained from theExpand
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HLA class I hyper-expression unmasks beta cells but not alpha cells to the immune system in pre-diabetes.
Human leukocyte antigens of class-I (HLA-I) molecules are hyper-expressed in insulin-containing islets (ICI) of type 1 diabetic (T1D) donors. This study investigated the HLA-I expression inExpand
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Infection à entérovirus in vitro et in vivo
Le genre Enterovirus comporte de nombreux virus a ARN non enveloppes regroupes en especes EV-A-J et Rhinovirus A-C. Les coxsackievirus B (CV-B) appartiennent a l’espece EV-B. Le role des CV-B etExpand
Overexpression of HLA class I predominantly on alpha cell in at risk individuals for type 1 diabetes
Human leukocyte antigens of class-I (HLA-I) molecules are hyper-expressed in insulin-containing islets (ICI) of type 1 diabetic (T1D) donors. This study investigated the HLA-I expression inExpand