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Etiology of community-acquired pneumonia treated in an ambulatory setting.
BACKGROUND Very few studies have addressed the etiology of community-acquired pneumonia (CAP) treated in an ambulatory setting. METHODS Patients were recruited from physicians' offices and from… Expand
Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors.
The glyconucleotides adenophostin A and B are the most potent known agonists at type 1 inositol trisphosphate [Ins(1,4,5)P3] receptors, although their stuctures differ markedly from that of… Expand
Incremental Ca2+ mobilization by inositol trisphosphate receptors is unlikely to be mediated by their desensitization or regulation by luminal or cytosolic Ca2+.
The kinetics of Ins(1,4,5)P3 (InsP3)-stimulated Ca2+ release from intracellular stores are unusual in that submaximal concentrations of InsP3 rapidly release only a fraction of the InsP3-sensitive… Expand
Luminal Ca2+ regulates passive Ca2+ efflux from the intracellular stores of hepatocytes.
Ca2+ uptake into the intracellular stores of permeabilized hepatocytes was entirely dependent on ATP and substantially inhibited by either ionomycin or thapsigargin, although both were required for… Expand
Lysine: N6-Hydroxylase: Stability and Interaction with Ligands
- S. Dick, L. Marrone, H. Duewel, M. Beecroft, J. McCourt, T. Viswanatha
- Biology, Medicine
- Journal of protein chemistry
- 1 November 1999
Recombinant lysine:N6-hydroxylase, rIucD, which is isolated as an apoenzyme, requires FAD and NADPH for its catalytic function. rIucD preparations have been found to undergo time-dependent loss in… Expand
Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy.
Adenophostin A is the most potent known agonist of D-myo-inositol 1, 4,5-trisphosphate [Ins(1,4,5)P3] receptors. Equilibrium competition binding studies with 3H-Ins(1,4,5)P3 showed that the… Expand
Resolution of symptoms in patients with community-acquired pneumonia treated on an ambulatory basis.
OBJECTIVE To describe the resolution of five symptoms commonly associated with community-acquired pneumonia (CAP). METHODS Three hundred and ninety-nine patients with CAP (Fine Classes I to III)… Expand
Symptom resolution in patients with Mycoplasma pneumoniae pneumonia.
- T. Marrie, M. Beecroft, Z. Herman-Gnjidic, M. Poulin-Costello
- Canadian respiratory journal
- 1 November 2004
BACKGROUND Mycoplasma pneumoniae generally causes pneumonia of mild to moderate severity in adults. However, little is known about the time course of the resolution of symptoms in this illness. … Expand