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Gateways to clinical trials.
TLDR
This issue focuses on the following selection of drugs: (Z)-4-Hydroxytamoxifen, [18F]-FPS, and the most recent clinical trials in current literature and congresses. Expand
Gateways to clinical trials.
TLDR
This issue focuses on the following selection of drugs: 101M. Expand
Pharmacokinetics and tolerability of a new low molecular mass heparin (RO-11) in healthy volunteers--a dose-finding study within the therapeutical range.
TLDR
The study focused on pharmacokinetics, dose-effect relationship and on tolerability of three single subcutaneous doses within the therapeutical range of RO-11, and found the compound was tolerated very well and no clinically relevant prolongation of APTT, prothrombin and thrombin clotting tests was observed. Expand
Gateways to clinical trials. March 2003.
Gateways to clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledgeExpand
Gateways to clinical trials.
TLDR
This issue focuses on the following selection of drugs: flurbiprofen, 90Yttrium-DOTA-huJ591, human papillomavirus vaccine, and parathyroid hormone. Expand
Sex-related pharmacokinetic and pharmacodynamic variations of lisinopril.
TLDR
Lisinopril was well tolerated and no significant sex-related differences were noted and pharmacokinetic and hemodynamic parameters were observed between males and females. Expand
Gateways to Clinical Trials: July-August 2002
TLDR
This issue focuses on the following selection of drugs: Aciclovir, alemtuzumab, alendronic acid sodium salt, alicaforsen sodium, alteplase, amifostine hydrate, antithymocyte globulin (equine), aspirin. Expand
Bioinversion of R(−)-Ketoprofen After Oral Administration in Healthy Volunteers
TLDR
The results of this study suggest that R(−)-ketoprofen undergoes limited, variable bioinversion to the S(+) antipode in humans, and if these findings are confirmed after oral administration of racemic ketofen, then a rationale exists for administering the S (+)-enantiomer per se rather than the racemic mixture. Expand
Gender related pharmacokinetics of diltiazem in healthy subjects.
TLDR
Female subjects showed higher values than females, but no significant difference was observed when comparing pharmacokinetic parameters by gender, and Diltiazem was well tolerated by all subjects. Expand
Gateways to clinical trials.
TLDR
This issues focuses on the following selection of drugs: (-)-Epigallocatechin gallate, (-)-gossypol, 2-deoxyglucose, 3-DAP, 7-monohydroxyethylrutoside. Expand
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