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Antimicrobial activity of the metals and metal oxide nanoparticles.
Books indicated that the particle size was the essential parameter which determined the antimicrobial effectiveness of the metal nanoparticles, and further studies should be performed to minimize the toxicity of metal and metal oxide nanoparticles to apply as proper alternatives for antibiotics and disinfectants especially in biomedical applications. Expand
Kinetic analysis of drug release from nanoparticles.
Considering the accuracy criteria the reciprocal powered time model could be suggested as a general model for analysis of multi mechanistic drug release from nanoparticles. Expand
Enhancement of dissolution rate of piroxicam using liquisolid compacts.
The results showed that liquisolid compacts demonstrated significantly higher drug release rates than those of conventionally made (capsules and directly compressed tablets containing micronized piroxicam) due to an increase in wetting properties and surface of drug available for dissolution. Expand
Predicting human intestinal permeability using single-pass intestinal perfusion in rat.
The SPIP could be utilized with precision to predict the human intestinal permeability and the fraction of dose absorbed following oral administration of drug in solution or regular release dosage form in human. Expand
The effect of type and concentration of vehicles on the dissolution rate of a poorly soluble drug (indomethacin) from liquisolid compacts.
The liquisolid compacts technique can be a promising alternative for the formulation of water insoluble drugs, such as indomethacin into rapid release tablets. Expand
Simultaneous determination of naproxen, ketoprofen and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation.
A simple reversed-phase high performance liquid chromatographic method with UV detection at 270 nm was developed for simultaneous quantitation of ketoprofen and naproxen sodium along with phenol redExpand
Biopharmaceutical classification of drugs using intrinsic dissolution rate (IDR) and rat intestinal permeability.
It is concluded that passively absorbed drugs could be categorized correctly based on their intrinsic dissolution rate (IDR) and intestinal permeability values. Expand
Piroxicam nanoparticles for ocular delivery: Physicochemical characterization and implementation in endotoxin-induced uveitis
It is proposed that the piroxicam:Eudragit®RS100 nanosuspensions may be considered as an improved ocular delivery system for locally inhibition of inflammation. Expand
Cogrinding as an approach to enhance dissolution rate of a poorly water-soluble drug (gliclazide)
Gliclazide is practically insoluble in water. In order to improve the drug dissolution rate, cogrinding method was used as an approach to prepare gliclazide coground/solid dispersions (SDs) in theExpand
Comparison of various cosolvency models for calculating solute solubility in water-cosolvent mixtures.
The combined nearly ideal binary solvent/Redlich-Kister, CNIBS/R-K, was found to be the best solution model in terms of its ability to describe the experimental solubility in mixed solvents. Expand