Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression
DCC may constitute a valid biomarker to identify those benign meningiomas at risk for progression based on its expression levels, and is identified as a predicted top upstream regulators beta-estradiol, TGFB1, Tgf beta complex, LY294002, and dexamethasone.
Efficacy of prone ventilation in adult patients with acute respiratory failure: a meta-analysis
The use of prone ventilation is associated with improved oxygenation, but it is not associated with a reduction in mortality, pneumonia, or ICU stay and may be associated with an increased incidence of pressure sores.
Incidence of Brain Tumours at an Academic Centre in Western Saudi Arabia
- M. Bangash
The results show that the overall incidence of brain tumours at KAUH was 6.0 x 105, in line with other studies that reported incidence rates ranging from 4.5 to 14.5 x105, within the range of international figures for brain tumour rates in both adults and children.
Comprehensive molecular biomarker identification in breast cancer brain metastases
- H. Schulten, M. Bangash, M. Al-Qahtani
- Biology, MedicineJournal of Translational Medicine
- 29 December 2017
Using complementary molecular genetic techniques, this study identified shared and unshared molecular events in three highly aberrant BCBM emphasizing the challenge to detect new molecular biomarkers and targets with translational implications.
Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines
Analysis of tissues and primary cell lines revealed stem cell associated genes as potential targets for aggressive and drug resistant meningiomas.
In situ characterization of stem cells-like biomarkers in meningiomas
Results strongly support the notion of heterogeneous populations of CSCs, even in grade I meningiomas, and call for the use of multiple markers for the accurate identification of individual CSC subgroups.
Microarray expression profiling identifies genes, including cytokines, and biofunctions, as diapedesis, associated with a brain metastasis from a papillary thyroid carcinoma.
- H. Schulten, D. Hussein, M. Al-Qahtani
- Biology, MedicineAmerican Journal of Cancer Research
- 1 October 2016
A set of candidate genes and biofunctions implicated in, so far nearly uncharacterized, molecular processes of a brain metastasis from a PTC are identified.
Epidemiological trends of histopathologically WHO classified CNS tumors in developing countries: systematic review.
Previously unreported trends of frequencies for individually classified CNS tumors were elucidated and a possible link of CNS tumors occurrence with geographical location emerged.
Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)
The Klinefelter syndrome, a new look to reproductive medicine in the era of genomics, and clinical implementation of pharmacogenomics for colorectal cancer treatment are highlighted.