Concentration of carbon dioxide, interstitial pH and synaptic transmission in hippocampal formation of the rat.
The results show that increasing the extracellular concentration of H+ ions has a moderately depressant effect on the firing threshold of hippocampal neurones and that the main effect of CO2 is on the electric excitability of postsynaptic cells.
Block of (Na+,K+)ATPase with ouabain induces spreading depression-like depolarization in hippocampal slices
Exogenous creatine delays anoxic depolarization and protects from hypoxic damage: dose–effect relationship
Kinetics of creatine in blood and brain after intraperitoneal injection in the rat
Electrophoretic characterization of gold nanoparticles functionalized with human serum albumin (HSA) and creatine.
Potential of creatine or phosphocreatine supplementation in cerebrovascular disease and in ischemic heart disease
Recent work showed that high-dose creatine supplementation causes an 8–9 % increase in cerebral creatine content, and that this is capable of improving, in humans, neuropsychological performances that are hampered by hypoxia, and animal work suggests that creatine supplementation may be protective in stroke.
Intracerebroventricular administration of creatine protects against damage by global cerebral ischemia in rat
Chlorpromazine protects brain tissue in hypoxia by delaying spreading depression-mediated calcium influx
Pathophysiology of anoxic depolarization: new findings and a working hypothesis
- M. Balestrino
- BiologyJournal of Neuroscience Methods
- 1 June 1995
Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage
Preliminary data show that creatine pretreatment decreases ischemic damage in vivo and causes an increase of cerebral phosphocreatine that has been shown to be of therapeutic value in vitro.