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Landscape of immune cell gene expression is unique in predominantly WHO grade 1 skull base meningiomas when compared to convexity
Modulation of tumor microenvironment is an emerging frontier for new therapeutics. However in meningiomas, the most frequent adult brain tumor, the correlation of microenvironment with tumorExpand
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“Skull base meningiomas have a distinct immune landscape.”
Modulation of tumor microenvironment is an emerging frontier for new therapeutics. However in meningiomas, the most frequent adult brain tumor, the correlation of microenvironment with tumorExpand
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Data Driven Analysis Reveals Shared Transcriptome Response, Immune Cell Composition, and Distinct Mortality Rates Across Differing Etiologies of Critical Illness
Supplemental Digital Content is available in the text. Objectives: Sepsis and trauma are common health problems and provide great challenges in critical care. Diverse patient responses to theseExpand
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Distinct regional ontogeny and activation of tumor associated macrophages in human glioblastoma
Tumor-associated macrophages (TAMs) constitute up to 50% of tumor bulk in glioblastoma (GBM) and play an important role in tumor maintenance and progression. The recently discovered differencesExpand
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BRAIN INJURY AFTER IMPACT : A CRITICAL BIBLIOGRAPHIC STUDY
Earlier Surgery Reduces Complications in Acute Traumatic Thoracolumbar Spinal Cord Injury: Analysis of a Multicenter Cohort of 4,108 Patients.
Early surgical intervention to decompress the spinal cord and stabilize the spinal column in patients with acute traumatic thoracolumbar spinal cord injury (TLSCI) may lessen the risk of developingExpand
Data driven analysis reveals shared transcriptome response and immune cell composition across aetiologies of critical illness
Sepsis and trauma are frequent and challenging health problems in critical care. The diversity of patient response to these conditions complicates both disease management and outcome prediction.Expand
Microenvironment of ruptured cerebral aneurysms discovered using data driven analysis of gene expression
Background It is well known that ruptured intracranial aneurysms are associated with substantial morbidity and mortality, yet our understanding of the genetic mechanisms of rupture remains poor. WeExpand