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Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model.
TLDR
Pharmacological evidence is provided that inhibiting sEH activity provides significant protection against islet β-cell damage and improves glucose homeostasis in STZ-induced diabetes. Expand
Vasorelaxant and hypotensive effects of a hydroalcoholic extract from the fruits of Nitraria sibirica Pall. (Nitrariaceae).
TLDR
This experimental animal study suggests that hydroalcoholic extract from the fruits of Nitraria sibirica Pall induces vasorelaxation through an endothelium-dependent pathway involving NO synthase activation, EDHF production and muscarinic receptor stimulation. Expand
A LC/QTOF-MS/MS application to investigate chemical compositions in a fraction with protein tyrosine phosphatase 1B inhibitory activity from Rosa rugosa flowers.
TLDR
The results suggest that this fraction of Rosa rugosa flowers extracted by ethyl acetate is a source of PTP1B inhibitory activity with a potential for treating diabetes. Expand
Separation and purification of two new and two known alkaloids from leaves of Nitraria sibirica by pH-zone-refining counter-current chromatography.
TLDR
The total alkaloids from Nitraria sibirica leaves have been confirmed to exhibit significant protective effects against inflammatory renal injury, hypertension and albuminuria in angiotensin II-salt hypertension and their structures were identified by ESI-MS, 1D and 2D NMR. Expand
Alkaloids of Nitraria sibirica Pall. decrease hypertension and albuminuria in angiotensin II-salt hypertension.
TLDR
Treatment with NSTA effectively reduces hypertension-induced albuminuria through the reduction of renal inflammatory and fibrosis markers. Expand
Phenolic glycosides from Nitraria sibirica leaves and their in vitro biological activities
TLDR
Nineteen phenolic glycosides were isolated from the Nitraria sibirica for the first time and presented strong inhibitory capacities against Candida albicans and strong antioxidant activity in bioactivity assays. Expand
Fatty Acids from Fritillaria pallidiflora and Their Biological Activity
Biological activity and LC-MS profiling of ethyl acetate extracts from Nitraria sibirica (Pall.) fruits
TLDR
Phytochemical profiles of the active extract will help the development and utilisation of N. sibirica in food and medicine and the potential antioxidant activity and protein tyrosine phosphatase 1B inhibitory activity of this plant are evaluated. Expand
Phenolic Compounds from Leaves of Nitraria sibirica
The Effect of Volatile Oil from Vernonia anthelmintica Seeds on Melanin Synthesis in B16 Cells and Its Chemical Analysis by GC-QTOF-MS
TLDR
According to the results, the AVO can promote melanogenesis and upregulate tyrosinase activity in B16 cells and can be used for leukoderma treatment in Xinjiang, China. Expand
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