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A Practical Two-Step Quantitative Clinical and Electrophysiological Assessment for the Diagnosis and Staging of Diabetic Neuropathy
TLDR
The results indicate that the MNSI is a good screening tool for diabetic neuropathy and that the MDNS coupled with nerve conductions provides a simple means to confirm this diagnosis.
The Warfarin-Aspirin Symptomatic Intracranial Disease Study
TLDR
A favorable risk/benefit ratio for warfarin compared with aspirin is suggested for the prevention of major vascular events in patients with symptomatic intracranial large-artery stenosis, and a prospective, randomized study is needed to confirm these findings.
Two-year incidence, remission, and change patterns of urinary incontinence in noninstitutionalized older adults.
TLDR
Patterns of urinary incontinence, its severity and types were studied by three sequential data collections at annual intervals and those who changed their severity level were most likely to progress from mild to moderate.
Ammonium perchlorate contamination of Colorado River drinking water is associated with abnormal thyroid function in newborns in Arizona.
TLDR
It is suggested that even low-level perchlorate contamination of drinking water may be associated with adverse health effects in neonates and highlights the need for both further study and control of human low- level per chlorate exposure.
Sexual function in the elderly.
TLDR
The consumption of at least one cup of coffee per day was significantly associated with aHigher prevalence of sexual activity in women and with a higher potency rate in men, and the prevalence of impotency was significantlyassociated with a history of heart attack, urinary incontinence, and a use of sedatives.
Prevalence of urinary incontinence and other urological symptoms in the noninstitutionalized elderly.
TLDR
The frequency of voiding was significantly increased among respondents with incontinence, or emptying or irritative symptoms compared to asymptomatic respondents, and these survey data are of importance to senior citizens, care providers and governmental agencies.
Nerve conduction measures in mild diabetic neuropathy in the Early Diabetes Intervention Trial
TLDR
The relationships between nerve conduction measures and age, sex, and anthropometric factors were similar for patients with type II, but not those with type I, diabetes to the relationships reported for normal subjects.
Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil.
TLDR
It is concluded that sorbinil, as a metabolic intervention targeted against a specific biochemical consequence of hyperglycemia, can improve the neuropathologic lesions of diabetic neuropathy.
Clinical and cystometric characteristics of continent and incontinent noninstitutionalized elderly.
TLDR
There is no significant association between uninhibited detrusor contractions and symptoms of difficult bladder emptying, irritative symptoms, voiding frequency, nocturia and urodynamic diagnosis of outlet obstruction but there were significant associations with responses to questions about the delay in getting to a toilet.
Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy
TLDR
Even low residual levels of aldose reductase activity may be neurotoxic in diabetes, and potent ARIs such as zenarestat may be required to stop or reverse progression of DPN, but >80% suppression of nerve sorbitol content is required.
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