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Development of a Drug Screening Platform Based on Engineered Heart Tissue
Rationale: Tissue engineering may provide advanced in vitro models for drug testing and, in combination with recent induced pluripotent stem cell technology, disease modeling, but availableExpand
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Modeling of Large-Scale Functional Brain Networks Based on Structural Connectivity from DTI: Comparison with EEG Derived Phase Coupling Networks and Evaluation of Alternative Methods along the
We investigate if phase-locking of fast oscillatory activity relies on the anatomical skeleton and if simple computational models informed by structural connectivity can help further to explain missing links in the structure-function relationship. Expand
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Herpes simplex virus–1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report
Relapsing symptoms post herpes simplex virus-1 (HSV) encephalitis (HSVE) usually occur a few weeks after viral therapy and represent either 1) a true viral relapse of HSVE (CSF PCR positive for HSV,Expand
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Structural Plasticity of Remote Cortical Brain Regions is Determined by Connectivity to the Primary Lesion in Subcortical Stroke
Cortical atrophy as demonstrated by measurement of cortical thickness (CT) is a hallmark of various neurodegenerative diseases. In the wake of an acute ischemic stroke, brain architecture undergoesExpand
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Sensorimotor Oscillatory Phase-Power Interaction Gates Resting Human Corticospinal Output.
Oscillatory activity within sensorimotor networks is characterized by time-varying changes in phase and power. The influence of interactions between sensorimotor oscillatory phase and power on humanExpand
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Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex
We developed and applied advanced mesoscopic (sub-millimeter) fMRI and analysis methodology to non-invasively investigate the functional organization topography across columnar and laminar structures in humans. Expand
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Voxel-based lesion-symptom mapping of stroke lesions underlying somatosensory deficits
The aim of this study was to investigate the relationship between stroke lesion location and the resulting somatosensory deficit. We studied exteroceptive and proprioceptive somatosensory symptomsExpand
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Cortico‐Cerebellar Structural Connectivity Is Related to Residual Motor Output in Chronic Stroke
Abstract Functional imaging studies have argued that interactions between cortical motor areas and the cerebellum are relevant for motor output and recovery processes after stroke. However, theExpand
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Enhanced Effective Connectivity Between Primary Motor Cortex and Intraparietal Sulcus in Well-Recovered Stroke Patients
Background and Purpose— Ischemic strokes with motor deficits lead to widespread changes in neural activity and interregional coupling between primary and secondary motor areas. Compared with frontalExpand
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A Rapid Form of Offline Consolidation in Skill Learning
The brain strengthens memories through consolidation, defined as resistance to interference (stabilization) or performance improvements between the end of a practice session and the beginning of theExpand
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