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Gene Ontology: tool for the unification of biology
The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
The genome sequence of Drosophila melanogaster.
The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map.
The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration
This work describes the OBO Foundry initiative and provides guidelines for those who might wish to become involved and describes an expanding family of ontologies designed to be interoperable and logically well formed and to incorporate accurate representations of biological reality.
FlyBase: enhancing Drosophila Gene Ontology annotations
Recent changes to the FlyBase GO annotation strategy that are improving the quality of the GO annotation data are described, including participation in the GO Reference Genome Annotation Project.
Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource
The Gene Ontology (GO) project provides structured, controlled vocabularies and classifications that cover several domains of molecular and cellular biology and are freely available for community use in the annotation of genes, gene products and sequences.
The Bacterial Symbiont Wolbachia Induces Resistance to RNA Viral Infections in Drosophila melanogaster
It is reported that a bacterial infection renders D. melanogaster more resistant to Drosophila C virus, reducing the load of viruses in infected flies and identifying these resistance-inducing bacteria as Wolbachia.
ChEBI: a database and ontology for chemical entities of biological interest
A dictionary of molecular entities focused on ‘small’ chemical compounds and an ontological classification, whereby the relationships between molecular entities or classes of entities and their parents and/or children are specified.
Historical Biogeography of the Drosophila melanogaster Species Subgroup
- D. Lachaise, M. Cariou, J. David, F. Lemeunier, L. Tsacas, M. Ashburner
- Biology, Environmental Science
Whereas there has been increasing interest in the eight members of the melanogaster species subgroup of Drosophila, no comprehensive survey exists of the biogeography and ecology of these species in…
Systematic determination of patterns of gene expression during Drosophila embryogenesis
Analyzing gene-expression patterns by in situ hybridization to whole-mount embryos provides an extremely rich dataset that can be used to identify genes involved in developmental processes that have been missed by traditional genetic analysis.