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An immunochemical analysis of oxytocin and vasopressin prohormone processing in vivo
Antisera against partially processed, unamidated forms of AVP and OT were raised and characterized by radioimmunoassay and immunocytochemistry. These antibodies, and antibodies that recognize fully… Expand
Backbone Cyclic Peptide Antagonists, Derived from the Insect Pheromone Biosynthesis Activating Neuropeptide, Inhibit Sex Pheromone Biosynthesis in Moths*
- M. Altstein, O. Ben-Aziz, S. Daniel, I. Schefler, I. Zeltser, C. Gilon
- Biology, Medicine
- The Journal of Biological Chemistry
- 18 June 1999
We describe an application of the backbone cyclization and cycloscan concept for the design and synthesis of pheromone biosynthesis activating neuropeptide (PBAN) antagonists capable of inhibiting… Expand
Advances in the application of neuropeptides in insect control
Abstract The development of a new approach for the generation of a novel type of putative insect control agents based on backbone cyclic peptidomimetic antagonists of insect-neuropeptides is… Expand
Purification and characterization of a paired basic residue-specific prohormone-converting enzyme from bovine pituitary neural lobe secretory vesicles.
- D. Parish, R. Tuteja, M. Altstein, H. Gainer, Y. P. Loh
- Medicine, Chemistry
- The Journal of biological chemistry
- 5 November 1986
The neuropeptides arginine vasopressin and oxytocin are generated from their prohormones in the hypothalamoneurohypophysial system by enzymatic cleavages at paired basic residues (i.e. Lys-Arg). This… Expand
Cloning and characterization of the pheromone biosynthesis activating neuropeptide receptor gene in Spodoptera littoralis larvae.
In noctuid moths cuticular pigmentation is regulated by the pyrokinin/pheromone biosynthesis activating neuropeptide (PK/PBAN) family, which also mediates a variety of other functions in moths and… Expand
Neuropeptide signaling in insects.
Neuropeptides represent the largest single class of signal compounds and are involved in regulation of development, growth, reproduction, metabolism and behavior of insects. Over the last few years… Expand
Novel insect control agents based on neuropeptide antagonists
- M. Altstein
- Medicine, Biology
- Journal of Molecular Neuroscience
This review describes the development of a new integrated approach to the generation of a novel type of insect neuropeptide (Np) antagonists and putative insect control agents based on… Expand
Insect neuropeptide antagonists.
- M. Altstein
- Chemistry, Medicine
The development of a new integrated approach to the generation of a novel type of insect neuropeptide (Np) antagonists and putative insect control agents based on backbone cyclic compounds is… Expand
Sol-gel matrixes doped with atrazine antibodies : Atrazine binding properties