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Influence of the Molecular Weight on the Inverse Temperature Transition of a Model Genetically Engineered Elastin-like pH-Responsive Polymer
The pH-responsive elastin-like polymers, [(PGVGV)2−(PGEGV)−(PGVGV)2]n with n = 5, 9, 15, 30, 45, were obtained using genetic engineering and microbial protein expression. These were intended to stu...
Biocompatibility of elastin-like polymer poly(VPAVG) microparticles: in vitro and in vivo studies.
TLDR
The results observed in this work suggested certain fibroblastic activity induced by poly(VPAVG) microparticles after their intraocular injection should be harnessed to preparemicroparticles loaded with an active substance.
Design and bioproduction of a recombinant multi(bio)functional elastin-like protein polymer containing cell adhesion sequences for tissue engineering purposes
TLDR
This work is framed in a long term project aimed to exploit the power of genetic engineering for the design and bioproduction of complex ECM analogues showing the rich complexity and multi (bio)functionality of the natural matrix.
Temperature-triggered self-assembly of elastin-like block co-recombinamers:the controlled formation of micelles and vesicles in an aqueous medium.
TLDR
The results obtained show how an evolution from a more common micellar structure to a hollow vesicle can be attained simply by changing the block arrangements and lengths, even when other molecular properties, such as molecular weight or mean polarity, remain essentially unchanged.
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