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Elastin-like recombinamer catalyst-free click gels: characterization of poroelastic and intrinsic viscoelastic properties.
Elastin-like recombinamer catalyst-free click gels (ELR-CFCGs) have been prepared and characterized by modifying both a structural ELR (VKVx24) and a biofunctionalized ELR-bearing RGD cell-adhesionExpand
“Recombinamers” as advanced materials for the post-oil age
Biotechnology offers powerful solutions to the challenges that arise during the design and development of new complex biomimetic materials to achieve specific biological responses. Recombinant DNAExpand
Influence of the Molecular Weight on the Inverse Temperature Transition of a Model Genetically Engineered Elastin-like pH-Responsive Polymer
The pH-responsive elastin-like polymers, [(PGVGV)2−(PGEGV)−(PGVGV)2]n with n = 5, 9, 15, 30, 45, were obtained using genetic engineering and microbial protein expression. These were intended to stu...
Developing functionality in elastin-like polymers by increasing their molecular complexity: the power of the genetic engineering approach
Abstract In spite of the enormous possibilities presented by macromolecules for the development of advanced materials with increased functionality, the achievement of functionality is often limitedExpand
Endothermic and exothermic components of an inverse temperature transition for hydrophobic association by TMDSC
Abstract Temperature modulated differential scanning calorimetry (TMDSC) has been used to study the phase separation process of three elastin-like model polymers; chemically synthesized poly(GVGVP)Expand
Design and bioproduction of a recombinant multi(bio)functional elastin-like protein polymer containing cell adhesion sequences for tissue engineering purposes
Genetic engineering techniques were used to design and biosynthesise an extracellular matrix (ECM) analogue. This was designed with a well-defined molecular architecture comprising differentExpand
Influence of the amino-acid sequence on the inverse temperature transition of elastin-like polymers.
This work explores the dependence of the inverse temperature transition of elastin-like polymers (ELPs) on the amino-acid sequence, i.e., the amino-acid arrangement along the macromolecule and theExpand
Synthesis and characterization of macroporous thermosensitive hydrogels from recombinant elastin-like polymers.
Multifunctional bioactive chemically cross-linked elastin-like polymers (ELPs) have been prepared as three-dimensional scaffolds for tissue engineering. The salt-leaching/gas-foaming technique wasExpand
Temperature-triggered self-assembly of elastin-like block co-recombinamers:the controlled formation of micelles and vesicles in an aqueous medium.
The possibility of obtaining different self-assembled nanostructures in reversible systems based on elastin-like block corecombinamers is explored in this work. The results obtained show how anExpand
Self-organized ECM-mimetic model based on an amphiphilic multiblock silk-elastin-like corecombinamer with a concomitant dual physical gelation process.
Although significant progress has been made in the area of injectable hydrogels for biomedical applications and model cell niches, further improvements are still needed, especially in terms ofExpand