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The Diagnosis of Mild Cognitive Impairment due to Alzheimer’s Disease: Recommendations from the National Institute on Aging-Alzheimer’s Association Workgroups on Diagnostic Guidelines for Alzheimer’s
TLDR
Criteria for the symptomatic predementia phase of Alzheimer’s disease (AD), referred to in this article as mild cognitive impairment due to AD, has four levels of certainty, depending on the presence and nature of the biomarker findings.
The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods
TLDR
The approach taken in ADNI to standardization across sites and platforms of the MRI protocol, postacquisition corrections, and phantom‐based monitoring of all scanners could be used as a model for other multisite trials.
Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease.
TLDR
The goal of this meeting was to propose guidelines that would enable clinicians to recognize patients with FTD and, if appropriate, expedite their referral to a diagnostic center.
Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
TLDR
It is hypothesized that there is a phase of increased medial temporal lobe activation early in the course of prodromal Alzheimer disease followed by a subsequent decrease as the disease progresses.
Social relationships, social support, and patterns of cognitive aging in healthy, high-functioning older adults: MacArthur studies of successful aging.
TLDR
Examination of the relationship of social ties and support to patterns of cognitive aging in the MacArthur Studies of Successful Aging suggests the potential value of further research on the role of the social environment in protecting against cognitive declines at older ages.
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