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Age-related changes in intracranial compartment volumes in normal adults assessed by magnetic resonance imaging.
Magnetic resonance (MR) image-based computerized segmentation was used to measure various intracranial compartments in 49 normal volunteers ranging in age from 24 to 80 years to determine age-relatedExpand
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The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI.
In this pilot study, algorithms for quantitatively evaluating the distribution and heterogeneity of human ventilation imaged with hyperpolarized (HP) (3)He MRI were developed for the goal ofExpand
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Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Mutations in the BRAF and KRAS genes occur in approximately 1% to 2% and 20% to 30% of non-small-cell lung cancer patients, respectively, suggesting that the mitogen-activated protein kinase (MAPK)Expand
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Intracranial compartment volumes in patients with enlarged ventricles assessed by magnetic resonance-based image processing.
Magnetic resonance image-based computerized segmentation was used to measure the volumes of the brain, gray and white matter components, and to identify regions with prolonged enhancement onExpand
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The Science of the Mind
  • M. Albert
  • Psychology, Medicine
  • Science
  • 14 March 1997
The author is associate professor of Psychiatry and Neurology at Harvard Medical School and director of the Gerontology Research Unit at Massachusetts General Hospital, Boston, MA. In his thoughtfulExpand
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Probing airway conditions governing ventilation defects in asthma via hyperpolarized MRI image functional modeling.
Image functional modeling (IFM) has been introduced as a method to simultaneously synthesize imaging and mechanical data with computational models to determine the degree and location of airwayExpand
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Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.
Tuberous sclerosis complex (TSC) is a familial tumor disorder for which there is no effective medical therapy. Disease-causing mutations in the TSC1 or TSC2 gene lead to increased mammalian target ofExpand
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Temporal dynamics of hyperpolarized 129Xe resonances in living rats.
temperature, with minimal loss of its hyperpolarization after Recent development of a magnetic-resonance technique sublimation. The hyperpolarized Xe gas was transferred using hyperpolarized nobleExpand
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Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen, and fluorinatedExpand
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MRI of stroke using hyperpolarized 129Xe
Because there is no background signal from xenon in biological tissue, and because inhaled xenon is delivered to the brain by blood flow, we would expect a perfusion deficit, such as is seen inExpand
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