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Morphology, function and isolation of halobacterial flagella.
Halobacterium halobium has right-handed helical flagella. During the logarithmic phase of growth, cells are predominantly monopolar, whereas in the stationary phase they are mostly bipolarlyExpand
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Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors.
  • R. Rose, Y. F. Gong, +6 authors P. Lin
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 20 February 1996
The observed in vitro and in vivo benefit of combination treatment with anti-human immunodeficiency virus (HIV) agents prompted us to examine the potential of resistance development when two proteaseExpand
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Signal transduction in the archaeon Halobacterium salinarium is processed through three subfamilies of 13 soluble and membrane-bound transducer proteins.
Eubacterial transducers are transmembrane, methyl-accepting proteins central to chemotaxis systems and share common structural features. We identified a large family of transducer proteins in theExpand
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Globin-coupled sensors: A class of heme-containing sensors in Archaea and Bacteria
  • S. Hou, T. Freitas, +7 authors M. Alam
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 31 July 2001
The recently discovered prokaryotic signal transducer HemAT, which has been described in both Archaea and Bacteria, mediates aerotactic responses. The N-terminal regions of HemAT from the archaeonExpand
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Methyl‐accepting taxis proteins in Halobacterium halobium.
Methyl‐accepting taxis proteins were identified and characterized in Halobacterium halobium, an archaebacterial species that is both chemotactic and phototactic. The data suggest direct involvementExpand
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An agarose-in-plug bridge method to study chemotaxis in the Archaeon Halobacterium salinarum.
  • H. S. Yu, M. Alam
  • Chemistry, Medicine
  • FEMS microbiology letters
  • 1 November 1997
A simple agarose-in-plug bridge method was developed to study chemotaxis in the Archaeon Halobacterium salinarum. Preheated liquid agarose solution with chemoeffectors is pipetted in the middle of aExpand
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Rotation and switching of the flagellar motor assembly in Halobacterium halobium.
Halobacterium halobium swims with a polarly inserted motor-driven flagellar bundle. The swimming direction of the cell can be reserved by switching the rotational sense of the bundle. The switch isExpand
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Structural features of methyl-accepting taxis proteins conserved between archaebacteria and eubacteria revealed by antigenic cross-reaction.
A number of eubacterial species contain methyl-accepting taxis proteins that are antigenically and thus structurally related to the well-characterized methyl-accepting chemotaxis proteins ofExpand
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Purification, reconstitution and polymorphic transition of halobacterial flagella.
Flagellar filaments of Halobacterium halobium have been purified by dissociation and reconstitution. Three different protein bands (23,500, 26,500 and 31,500 apparent molecular weight) are seen onExpand
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Purification of Aphanizomenon flos-aquae toxin and its chemical and physiological properties.
Abstract A toxin in chromatographically pure form has been isolated from natural blooms of the blue-green alga Aphanizomenon flos-aquae . The toxin is a strongly basic substance, which gives aExpand
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