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Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 Cells
- L. Al-Wahaibi, M. Al-Saleem, +7 authors G. Shazly
- Chemistry, MedicineInternational journal of molecular sciences
- 1 June 2020
Data indicates that conjugation of FLV to TAT (optimized formula) significantly enhances anti-proliferative activity and uptake by HepG2 cells when compared to raw FLV.
Contortisiliosides H–M: Triterpenoid saponins from Enterolobium contortisiliquum and their biological activity
- W. Abdel-Mageed, L. Al-Wahaibi, +6 authors M. Abdel-Kader
- ChemistryIndustrial Crops and Products
- 1 November 2019
Abstract Six new triterpenoid saponins, including four bisdesmosidic compounds, contortisiliosides H – K (1 – 4), and two monodesmosidic compounds, contortisiliosides L and M (7, 8), along with two…
A detailed study on chemical characterization of essential oil components of two Plectranthus species grown in Saudi Arabia
Abstract The chemical composition of the essential oils of Plectranthus cylindraceus and Plectranthus arabicus grown in Saudi Arabia were analyzed using gas chromatography techniques (GC–MS, GC–FID,…
A detailed study of the volatile components of Plectranthus asirensis of Saudi Arabian origin
- M. Al-Saleem, Merajuddin Khan, H. Alkhathlan
- Chemistry, MedicineNatural product research
- 23 March 2016
The results revealed that P. asirensis oil was mainly dominated by monoterpenoids in which most representative constituents were thymol, γ-terpinene, p-cymene and β-caryophyllene, the first report on the phytochemical constituents of P.Asirensis.
Phytochemical and chemotaxonomic study on Iris albicans Lange leaves
- Wael M Abdel-Mageed, L. Al-Wahaibi, M. Al-Saleem, Y. Gouda, M. Abdel-Kader, Z. Ibraheim
- 1 February 2018
Phytochemical investigation of the leaves of Iris albicans afforded eleven known compounds, including seven isoflavonoids and four xanthones, all of which were reported for the first time from I. albicans.
Biotechnological and Ecological Potential of Micromonospora provocatoris sp. nov., a Gifted Strain Isolated from the Challenger Deep of the Mariana Trench
Analysis of the genome sequence of strain MT25T revealed genes predicted to responsible for its adaptation to extreme environmental conditions that prevail in deep-sea sediments, including one responsible for the biosynthesis of desferrioxamine B.
Phytochemical standardization and biological activities of certain desert plants growing in Saudi Arabia
- M. Al-Saleem, A. Awaad, Monerah R. Alothman, S. Alqasoumi
- Biology, MedicineSaudi pharmaceutical journal : SPJ : the official…
- 13 December 2017
The phytochemical screening, antimicrobial and antitumor activities of Calendula tripterocarpa, Centarea sinaica, Centaurea pseudosinaica, Koelpinia linearis, Plectranthus arabicus, Plectranthus…
Flavonoid dimers from the aerial parts of Conyza stricta
A new flavonoid dimer, strictatin (10), was identified from the aerial part of Conyza stricta, in addition to eleven known compounds, and the chemotaxonomic significance of the identified metabolites was discussed.
Green synthesis, characterization, biological evaluation and docking study of some pyrazoline and pyrimidine derivatives
- H. Al-Ghulikah, A. El-Azab, M. Al-Saleem, M.S. AL-Towayan, S. A. Al‐Issa
- Research Journal of Chemistry and Environment
- 25 November 2021
Green and classical techniques have been utilized for preparing of a variety of aryl - substituted pyrazoline and pyrimidine derivatives (2-8). Reactions of chalcones 1 with semicarbazide and…
Secondary Metabolites from Two Plectranthus Species
Although Plectranthus species are known to produce varieties of important phytomolecules and considered to be a rich source of essential oils [1, 2], chemical studies of many Plectranthus species…