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Systemic sclerosis in 3 US ethnic groups: a comparison of clinical, sociodemographic, serologic, and immunogenetic determinants.
OBJECTIVE To determine whether ethnic factors influence the presentation, serologic expression and immunogenetics of systemic sclerosis (SSc), patients from 3 ethnic groups were compared for clinicalExpand
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Familial occurrence frequencies and relative risks for systemic sclerosis (scleroderma) in three United States cohorts.
OBJECTIVE To determine the frequency with which scleroderma (systemic sclerosis; SSc) recurs in families and the familial relative risk (lambda) in the US. METHODS Family histories of SSc wereExpand
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Amino acid sequence of the minor isomorph of the crustacean hyperglycemic hormone (CHH-II) of the Mexican crayfish Procambarus bouvieri (Ortmann): Presence of a d-amino acid
The primary structure of the neurohormone crustacean hyperglycemic hormone (CHH-II) was determined by means of enzymatic digestions, manual Edman degradation, and mass spectrometry. CHH-II is a 72Expand
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Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.
alpha-Conotoxins from marine snails are known to be selective and potent competitive antagonists of nicotinic acetylcholine receptors. Here we describe the purification, structural features andExpand
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Matrix metalloproteases from chondrocytes generate an antiangiogenic 16 kDa prolactin
The 16 kDa N-terminal fragment of prolactin (16K-prolactin) is a potent antiangiogenic factor. Here, we demonstrate that matrix metalloproteases (MMPs) produced and secreted by chondrocytes generateExpand
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Latent phenoloxidase activity and N-terminal amino acid sequence of hemocyanin from Bathynomus giganteus, a primitive crustacean.
N-terminal amino acid sequences for the two hemocyanin subunits from the deep-sea crustacean Bathynomus giganteus have been determined by Edman degradation, providing the first sequence informationExpand
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FMRFamide and related peptides in the phylum mollusca
FMRFamide is one of the well-known peptides studied within the phylum Mollusca. It was first isolated from the clam Macrocallista nimbosa during the end of the 1960s. Since then, a number of reportsExpand
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Identification, purification and initial characterization of the vitellogenesis-inhibiting hormone from the Mexican crayfish Procambarus bouvieri (Ortmann)
Abstract 1. 1. By means of a single step of RP-HPLC on μBondapak-Phenyl column, a neuropeptid with vutellogenesis-inhibiting hormone (VIH) activity was isolated from a crude extract of sinus glandsExpand
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A neuropeptide family from the sinus gland of the Mexican crayfish, Procambarus bouvieri (Ortmann)
Abstract The main neuroendocrine axis of crustaceans is constituted by the brain, medulla terminalis X-organ (MTXO) -sinus gland (SG) system. A variety of hormonal peptides are synthesized in theExpand
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Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes
An impressive biodiversity (>10,000 species) of marine snails (suborder Toxoglossa or superfamily Conoidea) have complex venoms, each containing approximately 100 biologically active, disulfide‐richExpand
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