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Oxidative Stress and Pathogenesis of Inflammatory Bowel Disease: An Epiphenomenon or the Cause?
Crohn’s disease (CD) and ulcerative colitis (UC), known as inflammatory bowel disease (IBD), are fairly common chronic inflammatory conditions of the gastrointestinal tract. Although the exactExpand
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A review on the role of antioxidants in the management of diabetes and its complications.
Diabetes is a prevalent systemic disease affecting a significant proportion of the population worldwide. The effects of diabetes are devastating and well documented. There is increasing evidence thatExpand
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Biochemical evidence for free radicalinduced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats
Organophosphorus compounds may induce oxidative stress leading to generation of free radicals and alterations in antioxidant and scavengers of oxygen free radicals (OFRs). The effect of subchronicExpand
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Tramadol intoxication: a review of 114 cases
Tramadol as a centrally acting analgesic is extensively used in the management of moderate to severe pain. It slightly affects opioid receptors and inhibits the reuptake of norepinephrin andExpand
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A Systematic Review of Aluminium Phosphide Poisoning
A Systematic Review of Aluminium Phosphide Poisoning Every year, about 300,000 people die because of pesticide poisoning worldwide. The most common pesticide agents are organophosphates andExpand
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Induction of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers
Oxidative stress status and acetylcholinesterase (AChE) activity were studied in blood samples obtained from 45 organophosphorous (OP)-formulating pesticide workers with a minimum work history of 1Expand
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Dose-independent occurrence of seizure with tramadol
IntroductionTramadol, as a centrally-acting, opioid-like analgesic with serotonin reuptake inhibition property, is one of the most prescribed analgesics in the world. We assessed the incidence ofExpand
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Factors Related to Seizure in Tramadol Poisoning and Its Blood Concentration
This study examines the relation between seizure and plasma tramadol concentration in patients with tramadol poisoning, as a novel centrally acting analgesic used for the treatment of mild to severeExpand
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Toxicological and pharmacological concerns on oxidative stress and related diseases.
Although reactive oxygen species (ROS) such as superoxide, hydrogen peroxide and hydroxyl radical are generated as the natural byproduct of normal oxygen metabolism, they can create oxidative damageExpand
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The Story of Beta-sitosterol-A Review
Aims : Phytosterols are a subgroup of the steroids, as an important class of bioorganic molecules,widespread in plants, animals, marines as well as fungi and have similarity to cholesterol inExpand
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