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Selective Effect of 2′,6′-Dihydroxy-4′-Methoxychalcone Isolated from Piper aduncum on Leishmania amazonensis
Observations suggest that DMC is selectively toxic to the parasites, and its simple structure may well enable it to serve as a new lead compound for the synthesis of novel antileishmanial drugs. Expand
Antimicrobial activity in vitro of plumbagin isolated from Plumbago species.
The naphthoquinone plumbagin is suggested as a promising antimicrobial agent against bacteria and yeast. Expand
Essential oil analysis of 10 Piperaceae species from the Brazilian Atlantic forest.
A great number of non-oxygenated monoterpenes and sesquiterpenes are derived from E,E-farnesyl-PP, suggesting a preference of these species to synthesize metabolites from this pathway. Expand
Biosynthesis significance of iridoids in chemosystematics
Iridoids represent a large group of monoterpenoid compounds that apparently seem to be formed in plants by an alternative cyclization of geranyl diphosphate. The structures of these compounds areExpand
Chemical study and larvicidal activity against Aedes aegypti of essential oil of Piper aduncum L. (Piperaceae).
The essential oil from leaves of P. aduncum collected in the Brazilian Cerrado, North of Minas Gerais, as well as to evaluate the larvicidal activity of this oil and of its major constituent 1,8-cineole, showed to be very different from those obtained from the same species. Expand
Anthelmintic activity of the latex of Ficus species.
The observed high acute toxicity with hemorrhagic enteritis, in addition to a weak anthelmintic efficacy, do not recommend the use of these lattices in traditional medicine. Expand
Potential cytotoxic activity of some Brazilian seaweeds on human melanoma cells
In vitro screening of the crude extracts of some Brazilian coastal seaweeds for cytotoxic activity against a cultured human melanoma cancer cell line using the sulphorhodamine B assay was performed.Expand
Vasodilator Activity of the Essential Oil from Aerial Parts of Pectis brevipedunculata and Its Main Constituent Citral in Rat Aorta
EOPB and citral elicited vasorelaxation on thoracic aorta by affecting the NO/cyclic GMP pathway and the calcium influx through voltage-dependent l-type Ca2+ channels, respectively. Expand
Plumbagin quantification in roots of Plumbago scandens L. obtained by different extraction techniques.
Plumbagin was always the major component in all analyzed extracts and it was quantitatively determined by gas chromatograph coupled with mass spectrometer, Soxhlet was the most efficient extraction technique however, prolonged heating time promoted plumbagin degradation. Expand
Chemical composition and efficacy in the egg-hatching inhibition of essential oil of Piper aduncum against Haemonchus contortus from sheep
The essential oil showed to be effective in inhibiting H. contortus hatchability and the LC90 was calculated as 8.9 mg.ml-1.ml, which can point out the P. aduncumessential oil and its chemical components as potential alternative to control of H.contortus. Expand