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Crystal structure of potato tuber ADP‐glucose pyrophosphorylase
ADP‐glucose pyrophosphorylase catalyzes the first committed and rate‐limiting step in starch biosynthesis in plants and glycogen biosynthesis in bacteria. It is the enzymatic site for regulation ofExpand
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ADP-Glucose Pyrophosphorylase, a Regulatory Enzyme for Bacterial Glycogen Synthesis
SUMMARY The accumulation of α-1,4-polyglucans is an important strategy to cope with transient starvation conditions in the environment. In bacteria and plants, the synthesis of glycogen and starchExpand
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Mechanism of Reductive Activation of Potato Tuber ADP-glucose Pyrophosphorylase*
The potato tuber (Solanum tuberosumL.) ADP-glucose pyrophosphorylase activity is activated by a incubation with ADP-glucose and dithiothreitol or by ATP, glucose- 1-phosphate, Ca2+, andExpand
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Two Arabidopsis ADP-Glucose Pyrophosphorylase Large Subunits (APL1 and APL2) Are Catalytic1
ADP-glucose (Glc) pyrophosphorylase (ADP-Glc PPase) catalyzes the first committed step in starch biosynthesis. Higher plant ADP-Glc PPase is a heterotetramer (α2β2) consisting of two small and twoExpand
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Activation of the Potato Tuber ADP-glucose Pyrophosphorylase by Thioredoxin*
The potato tuber (Solanum tuberosumL.) ADP-glucose pyrophosphorylase (ADP-GlcPPase) catalyzes the first committed step in starch biosynthesis. The main type of regulation of this enzyme isExpand
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The Different Large Subunit Isoforms of Arabidopsis thaliana ADP-glucose Pyrophosphorylase Confer Distinct Kinetic and Regulatory Properties to the Heterotetrameric Enzyme*
ADP-glucose pyrophosphorylase catalyzes the first and limiting step in starch biosynthesis and is allosterically regulated by the levels of 3-phosphoglycerate and phosphate in plants. ADP-glucoseExpand
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ADP-Glucose Pyrophosphorylase: A Regulatory Enzyme for Plant Starch Synthesis
In plants, the synthesis of starch occurs by utilizing ADP-glucose as the glucosyl donor for the elongation of α-1,4-glucosidic chains. In photosynthetic bacteria the synthesis of glycogen follows aExpand
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Adenosine 5[prime]-Diphosphate-Glucose Pyrophosphorylase from Potato Tuber (Significance of the N Terminus of the Small Subunit for Catalytic Properties and Heat Stability)
cDNAs encoding the large subunit and a possibly truncated small subunit of the potato tuber (Solanum tuberosum L.) adenosine 5[prime]-diphosphate-glucose pyrophosphorylase have been expressed inExpand
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Resurrecting the Ancestral Enzymatic Role of a Modulatory Subunit*♦
In the post-genomic era, functional prediction of genes is largely based on sequence similarity searches, but sometimes the homologues bear different roles because of evolutionary adaptations. ForExpand
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ADP-Glucose pyrophosphorylase from potato tubers. Site-directed mutagenesis studies of the regulatory sites.
Several lysines (Lys) were determined to be involved in the regulation of the ADP-glucose (Glc) pyrophosphorylase from spinach leaf and the cyanobacterium Anabaena sp. PCC 7120 (K. Ball, J. PreissExpand
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