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Everted gut sac model as a tool in pharmaceutical research: limitations and applications
Objectives  This review discusses the limitations and applications of the everted gut sac model in studying drug absorption, metabolism, and interaction.
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Modulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resin
Present study investigated the potential effects of Ferula asafetida resin on metabolic activities of human drug metabolizing enzymes: CYP2D6 and CYP3A4. Dextromethorphan (DEX) was used as a markerExpand
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Solid dispersions: a strategy for poorly aqueous soluble drugs and technology updates
Introduction: Present article reviews solid dispersion (SD) technologies and other patented inventions in the area of pharmaceutical SDs, which provide stable amorphous SDs. Areas covered: The reviewExpand
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Rhodamine-123: a p-glycoprotein marker complex with sodium lauryl sulfate.
Aim of this study was to investigate the role of sodium lauryl sulfate (SLS) as P-glycoprotein inhibitor. The everted rat gut sac model was used to study in-vitro mucosal to serosal transport ofExpand
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Formulation and characterization of novel soft nanovesicles for enhanced transdermal delivery of eprosartan mesylate
The objective of the present work was to formulate, optimize and evaluate the potential of novel soft nanovesicles i.e. nano-transfersomes, containing eprosartan mesylate (EM) for transdermalExpand
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Development and evaluation of acid-buffering bioadhesive vaginal tablet for mixed vaginal infections
An acid-buffering bioadhesive vaginal tablet was developed for the treatment of genitourinary tract infections. From the bioadhesion experiment and release studies it was found that polycarbophil andExpand
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Development and in vitro evaluation of an acid buffering bioadhesive vaginal gel for mixed vaginal infections
Development and in vitro evaluation of an acid buffering bioadhesive vaginal gel for mixed vaginal infections An acid buffering bioadhesive vaginal (ABBV) gel was developed for the treatment of mixedExpand
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Protective effects of Punica granatum in experimentally-induced gastric ulcers
In the present investigation standardized aqueous methanolic extract of Punica (AMP) was used for its possible ulcer protective activity in wistar rats against different experimental models.Expand
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Pharmacodynamic study of eprosartan mesylate-loaded transfersomes Carbopol® gel under Dermaroller® on rats with methyl prednisolone acetate-induced hypertension.
The objective of present study was to prepare eprosartan mesylate (EM)-loaded transfersomes Carbopol® gel and characterized for various parameters, including in vitro skin permeation, in vivoExpand
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Effect of Trigonella foenum-graecum L. on Metabolic Activity of CYP2D6 and CYP3A4
Background: The present study investigated the effect of fenugreek seeds powder and its alcoholic extract on metabolic activity of drug-metabolizing enzymes CYP2D6 and CYP3A4. Materials and Methods:Expand
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