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Bioprospecting of South African Plants as a Unique Resource for Bioactive Endophytic Microbes
South Africa has a long history and strong belief in traditional herbal medicines. Using ethnobotanical knowledge as a lead, a large number of South African medicinal plants have been discovered toExpand
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Anti-inflammatory and antioxidant properties of leaf extracts of eleven South African medicinal plants used traditionally to treat inflammation.
ETHNOPHARMACOLOGICAL RELEVANCE Inflammation is a complex mechanism employed by the body to promote healing and restoration to normal function in the event of injury. Eleven plant species wereExpand
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South African medicinal plant extracts active against influenza A virus
BackgroundInfluenza infection remains a major health threat for animals and humans which crucially requires effective antiviral remedies. The usage of herbal medications as readily availableExpand
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Immunomodulatory properties of quercetin-3-O-α-L-rhamnopyranoside from Rapanea melanophloeos against influenza a virus
BackgroundInfluenza infection is a major public health threat. The role of influenza A virus-induced inflammatory response in severe cases of this disease is widely recognized. Drug resistance andExpand
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Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review
Peptides are important biomolecules which facilitate the understanding of complex biological processes, which in turn could be serendipitous biological targets for future drugs. They are classifiedExpand
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The potential use of leaf extracts of two Newtonia (Fabaceae) species to treat diarrhoea
Abstract In southern Africa, many medicinal plants are used traditionally to treat gastrointestinal disorders and other infectious diseases. Newtonia hildebrandtii and Newtonia buchananii are usedExpand
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A comprehensive study of the potential phytomedicinal use and toxicity of invasive Tithonia species in South Africa
BackgroundTithonia diversifolia and T. rotundifolia belong to the Asteraceae family and are native to Mexico and Central America. These plants have become invasive in parts of tropical Africa andExpand
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Microbial communication: A significant approach for new leads
Abstract A significant number of naturally occurring secondary metabolites from plants and microbes have been explored for their pharmacological properties and used as drugs, for example to combatExpand
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Isolation of endophytic fungi from South African plants, and screening for their antimicrobial and extracellular enzymatic activities and presence of type I polyketide synthases
Abstract Endophytes are bacteria or fungi which live inside the host plant and participate in many biological processes without causing disease or other adverse effects. Endophytes are recognised asExpand
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