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Characterising the biology of novel lytic bacteriophages infecting multidrug resistant Klebsiella pneumoniae
BackgroundMembers of the genus Klebsiella are among the leading microbial pathogens associated with nosocomial infection. The increased incidence of antimicrobial resistance in these species hasExpand
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Efficacy and Safety of a Bovine-Associated Staphylococcus aureus Phage Cocktail in a Murine Model of Mastitis
Overuse of antibiotics is a major problem in the treatment of bovine mastitis, and antibiotic treatment is frequently non-curative, thus alternative treatments are necessary. The primary aim of thisExpand
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Phages in the global fruit and vegetable industry
From recent articles, we have learned that phages can constitute a promising alternative in the food industry to eliminate bacterial pathogens from seedlings in greenhouse and field environments, asExpand
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Phage neutralization by sera of patients receiving phage therapy.
The aim of our investigation was to verify whether phage therapy (PT) can induce antiphage antibodies. The antiphage activity was determined in sera from 122 patients from the Phage Therapy Unit inExpand
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Prospects of Phage Application in the Treatment of Acne Caused by Propionibacterium acnes
Propionibacterium acnes is associated with purulent skin infections, and it poses a global problem for both patients and doctors. Acne vulgaris (acne) remains a problem due to its chronic characterExpand
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Bacteriophage Procurement for Therapeutic Purposes
Bacteriophages (phages), discovered 100 years ago, are able to infect and destroy only bacterial cells. In the current crisis of antibiotic efficacy, phage therapy is considered as a supplementary orExpand
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Antibody Production in Response to Staphylococcal MS-1 Phage Cocktail in Patients Undergoing Phage Therapy
In this study, we investigated the humoral immune response (through the release of IgG, IgA, and IgM antiphage antibodies) to a staphylococcal phage cocktail in patients undergoing experimental phageExpand
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Antiphage activity of sera during phage therapy in relation to its outcome.
AIM The aim was to study the association between the phage neutralization of patients' sera and the clinical outcome of phage therapy (PT). PATIENTS About 62 patients with various bacterialExpand
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The Effect of Bacteriophage Preparations on Intracellular Killing of Bacteria by Phagocytes
Intracellular killing of bacteria is one of the fundamental mechanisms against invading pathogens. Impaired intracellular killing of bacteria by phagocytes may be the reason of chronic infections andExpand
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The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration
BackgroundThe antibacterial activity of bacteriophages has been described rather well. However, knowledge about the direct interactions of bacteriophages with mammalian organisms and their other,Expand
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