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- Publications
- Influence
Interleukin-35 is upregulated in systemic sclerosis and its serum levels are associated with early disease.
OBJECTIVES
IL-35 is a member of the IL-12 family consisting of p35/IL-12a and EBI3/IL-27b subunits. IL-35 exerts immunomodulatory activities in experimental and human autoimmune inflammatory… Expand
Clinical improvement and reduction in serum calprotectin levels after an intensive exercise programme for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis
- A. Levitová, H. Hulejová, M. Špiritović, K. Pavelka, L. Šenolt, M. Husakova
- Medicine
- Arthritis Research & Therapy
- 25 November 2016
BackgroundThe efficacy of exercise therapy for ankylosing spondylitis (AS) is well-documented, but dearth of information is for non-radiographic axial spondyloarthritis (nr-axSpA).Biomarkers like… Expand
Alterations in activin A-myostatin-follistatin system associate with disease activity in inflammatory myopathies.
- L. Vernerová, V. Horváthová, +13 authors J. Vencovský
- Medicine
- Rheumatology
- 28 January 2020
OBJECTIVES
The aim of this study was to investigate the systemic and skeletal muscle levels of atrophy-associated myokines in patients with idiopathic inflammatory myopathies (IIM) and their… Expand
Altered dynamics of lipid metabolism in muscle cells from patients with idiopathic inflammatory myopathy is ameliorated by 6 months of training
- M. Nemec, L. Vernerová, +11 authors B. Ukropcová
- Medicine
- The Journal of physiology
- 16 October 2020
Regular exercise improves muscle functional capacity and clinical state of patients with idiopathic inflammatory myopathy (IIM). In our study, we used an in vitro model of human primary muscle cell… Expand
Changes of patient-reported outcomes and protein fingerprint biomarkers after exercise therapy for axial spondyloarthritis
- M. Husakova, A. Siebuhr, K. Pavelka, M. Špiritović, A. Bay-Jensen, A. Levitová
- Medicine
- Clinical Rheumatology
- 2017
The objective of this study was to investigate the patient-reported outcomes (PROs) and matrix metalloproteinase (MMP) derived extracellular matrix (ECM) biomarkers in non-radiographic (nr)-axial… Expand
Comparison of Deep Tissue Massage and Therapeutic Massage for Lower Back Pain, Disease Activity, and Functional Capacity of Ankylosing Spondylitis Patients: A Randomized Clinical Pilot Study
- M. Romanowski, M. Špiritović, R. Rutkowski, A. Dudek, W. Samborski, A. Straburzyńska-Lupa
- Medicine
- Evidence-based complementary and alternative…
- 6 August 2017
Objectives This study aims to compare the effectiveness of deep tissue massage (DTM) and therapeutic massage (TM) in the management of ankylosing spondylitis (AS) patients. Materials and Methods This… Expand
A3.10 Plasma levels of heat shock protein 90 correlate with disease activity, lung involvement and skin fibrosis in systemic sclerosis
- H. Štorkánová, H. Hulejová, +8 authors M. Tomčík
- Medicine
- 13 February 2015
Background Our previous study demonstrated that Heat shock protein 90 (Hsp90) is overexpressed in the skin of patients with systemic sclerosis (SSc), in cultured SSc fibroblasts and preclinical… Expand
AB0687 EFFECTIVENESS OF SPECIALIZED AND INTENSIVE ADL TRAINING IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES – PRELIMINARY RESULTS OF A ONE-YEAR CONTROLLED STUDY
- M. Špiritović, S. Oreská, +12 authors M. Tomčík
- Medicine
- 1 June 2019
Background Idiopathic inflammatory myopathy are characterized by muscle weakness, caused by inflammation and immune changes in the affected muscles, which lead to a limitation in the execution of… Expand
AB0799 Alterations of body composition in scleroderma patients are associated with disease activity and physical activity but not with lung involvement
- S. Oreská, M. Špiritović, +11 authors M. Tomčík
- Medicine
- 1 June 2018
Background Systemic sclerosis (SSc) is characterised by fibrosis of the skin and visceral organs, especially digestive tract, and musculoskeletal and lung involvement, which limit… Expand
SAT0483 Female sexual dysfunction in patients with systemic sclerosis
- B. Heřmánková, M. Špiritović, +7 authors M. Tomčík
- Medicine
- 1 June 2018
Background Systemic sclerosis (SSc) is a chronic autoimmune disease leading to various physical and psychological impairments including sexual dysfunction. Objectives To assess sexual… Expand