M Walla-Friedel

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A higher frequency of a variant of the angiotensinogen gene characterized by a transition in exon 2 causing a replacement of methionine by threonine (M235T) has recently been found in hypertensive individuals, but not all authors were able to confirm this observation. We examined (i) 219 patients with primary hypertension, (ii) 92 normotensive controls(More)
BACKGROUND A mutation in the gene for the angiotensin II type 1 (AT1) receptor (A1166C) has been reported to be associated with primary hypertension. OBJECTIVE To determine whether this observation could be confirmed with a different population sample. DESIGN We examined 414 individuals with primary hypertension and 172 normotensive controls. METHODS(More)
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