It has been previously demonstrated that gabapentin, a gamma-amino butyric acid analogue, inhibits monoaminergic neurotransmitter release from rabbit caudate nucleus slices and from rat cortex. In humans this drug has been shown to have anti-epileptogenic activity. Serotonin may act as an inhibitory neurotransmitter and its interaction with blood platelets… (More)
We present the case of a 42-year-old man who complained of low back pain radiating into the posterior aspect of both thighs. There were no neurological deficits, while general medical examination revealed a Cushing's syndrome due to corticosteroid therapy for rheumatic polyarthritis. Myelography showed irregular and circumferential narrowing of the dural… (More)
The value of T2-weighted fast spin-echo imaging of the musculoskeletal system was assessed in 22 patients with various neoplastic, inflammatory, and traumatic disorders. Images were acquired with high echo number (i.e., echo train length) fast spin-echo (FSE; TR 2000 ms, effective TE 100 ms, echo number 13, linear k-space ordering), conventional spin-echo… (More)
Signal intensities, signal-to-noise ratios (S/N), and contrast-to-noise ratios (C/N) in dependence on the echo distance and echo number of the new turbo (fast) spin-echo technique are analysed by phantom, volunteer and patient measurements. With increasing echo number (3 to 15 echoes), signal intensities increase (25 to 50%), S/N varies between different… (More)
Axial MR images of the shoulder joint reveal a central linear band within the supraspinatus muscle void of signal which seems not to represent the only tendon of this muscle. Due to the importance of the supraspinatus muscle for the painful impingement syndrome of the shoulder we studied the fibrous architecture of this muscle comparing 30 MR images and 49… (More)
A zone of increased signal intensity seen in asymptomatic subjects near the insertion of the supraspinous tendon onto the greater tuberosity ("pseudogap") leads to difficulty in the interpretation of magnetic resonance (MR) images of the shoulder. To better understand this pseudogap, the authors dissected and sectioned the shoulders of four cadavers and… (More)
Function and usage of the graphic-software "MacDraw" is described and illustrated by drawing a lumbar vertebrae and pathologic clefts in a layer technique.