M V Spampinato

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BACKGROUND AND PURPOSE Despite being the gold standard technique for stroke assessment, conventional diffusion MRI provides only partial information about tissue microstructure. Diffusional kurtosis imaging is an advanced diffusion MRI method that yields, in addition to conventional diffusion information, the diffusional kurtosis, which may help improve(More)
BACKGROUND It has been hypothesised that seizure induced neuronal loss and axonal damage in medial temporal lobe epilepsy (MTLE) may lead to the development of aberrant connections between limbic structures and eventually result in the reorganisation of the limbic network. In this study, limbic structural connectivity in patients with MTLE was investigated,(More)
We assessed political attitudes using the Implicit Association Test (IAT) in which participants were presented faces and names of well-known Democrat and Republican politicians along with positive and negative words while undergoing functional MRI. We found a significant behavioral IAT effect for the face, but not the name, condition. The fMRI face(More)
We conducted an event-related, functional MRI investigation of 12 male's and 12 female's reasoning about conditional deontic rules, rules regulating people's behavior. We employed two different types of rules: social contracts and nonsocial, precautionary rules. Although the rules and the demands of the task were matched in terms of their logical structure,(More)
BACKGROUND AND PURPOSE Along with cortical abnormalities, white matter microstructural changes such as axonal loss and myelin breakdown are implicated in the pathogenesis of Alzheimer disease. Recently, a white matter model was introduced that relates non-Gaussian diffusional kurtosis imaging metrics to characteristics of white matter tract integrity,(More)
BACKGROUND Dural sinus malformations are rare congenital forms of dural arteriovenous shunt. Our goal is to describe prenatal ultrasonography and magnetic resonance imaging (MRI) findings of a thrombosed midline dural venous malformation. CASE Second-trimester fetal ultrasonography and MRI demonstrated a large T2-hypointense mass centered at the level of(More)
The adenohypophysis and neurohypophysis originate from the combination of 2 events occurring during the fourth week of life, the development of Rathke pouch and of a neuroectodermal evagination of tissue from the floor of the diencephalon. Congenital pathology of the pituitary gland and parasellar regions derives from abnormalities of these coordinated(More)
Only a subset of adults acquires specific advanced mathematical skills, such as integral calculus. The representation of more sophisticated mathematical concepts probably evolved from basic number systems; however its neuroanatomical basis is still unknown. Using fMRI, we investigated the neural basis of integral calculus while healthy participants were(More)
OBJECTIVE The purpose of this study was to determine whether perfusion-weighted imaging (PWI) and proton MR spectroscopy (MRS) are useful in differentiating high- and low-grade oligodendroglial tumors. MATERIALS AND METHODS PWI and MRS studies of 22 patients with histologically proven oligodendroglioma or oligoastrocytoma (13 low-grade and nine anaplastic(More)
BACKGROUND AND PURPOSE Current classification and grading of primary brain tumors has significant limitations. Our aim was to determine whether the relative cerebral volume (rCBV) measurements in gliomas may serve as an adjunct to histopathologic grading, with a hypothesis that rCBV values are more accurate in predicting 1-year survival and recurrence. (More)