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AIM OF THE STUDY To investigate the effect of in vivo short-term ethanol administration (i.p., 1.5 g/kg, 6 h) on binding characteristics of opioid receptor agonists in rat midbrain, as well as the contents of dopamine, serotonin and their precursors and metabolites in midbrain, striatum and hypothalamus of rats after long-term alcohol consumption. The… (More)
In this work we investigated the content of opioids in plasma blood and the changes caused by ethanol (1.5 g/kg, i.p.) in midbrain opioid receptors of rats with different sensitivity to ethanol, as determined according to the duration of ethanol-induced sleep (DEIS). A receptor binding technique with selective delta-DADLE and mu-DAGO radioligands were used.… (More)