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Antibody drug conjugates (ADCs) are a multi-component modality comprising of an antibody targeting a cell-specific antigen, a potent drug/payload, and a linker that can be processed within cellular compartments to release payload upon internalization. Numerous ADCs are being evaluated in both research and clinical settings within the academic and(More)
BACKGROUND AND OBJECTIVES Pneumonia with Acinetobacter baumannii has a major therapeutic problem in health care settings. Decision to initiate correct antibiotic therapy requires rapid identification and quantification of organism. The aim of this study was to develop a rapid and sensitive method for direct detection of A. baumannii from respiratory(More)
The recently established Neural Engineering Data Consortium (NEDC) is in the process of developing its first large-scale corpus. This corpus, known as the Temple University Hospital EEG Corpus, upon completion, will total over 20,000 EEG studies, and include patient information, medical histories and physician assessments, making it the largest and most(More)
OBJECTIVE Biotin is a coenzyme composed of four carboxylases. It presents in amino acid catabolism, fatty acid synthesis, and gluconeogenesis. Biotinidase recycles the vitamin biotin. A biotinidase deficiency is a neurocutaneous disorder with autosomal recessive inheritance. The symptoms can be successfully treated or prevented by administering(More)
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