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BACKGROUND Due to the limited number of experimental studies that mechanically characterise human atherosclerotic plaque tissue from the femoral arteries, a recent trend has emerged in current literature whereby one set of material data based on aortic plaque tissue is employed to numerically represent diseased femoral artery tissue. This study aims to(More)
OBJECTIVE To provide a clinically useful analysis of the relationship between selective serotonin reuptake inhibitors (SSRIs), in particular fluoxetine and violent or suicidal behaviour. METHOD All published papers on Medline and other databases linking serotonin, SSRIs and aggression were reviewed. RESULTS A small proportion of patients treated with(More)
Stimulated by a recent controversy regarding pressure drops predicted in a giant aneurysm with a proximal stenosis, the present study sought to assess variability in the prediction of pressures and flow by a wide variety of research groups. In phase I, lumen geometry, flow rates, and fluid properties were specified, leaving each research group to choose(More)
BACKGROUND Abdominal aortic aneurysms (AAA) are local dilatations of the infrarenal aorta. If left untreated they may rupture and lead to death. One form of treatment is the minimally invasive insertion of a stent-graft into the aneurysm. Despite this effective treatment aneurysms may occasionally continue to expand and this may eventually result in(More)
3. A model to predict deflection of bevel-tipped active needle advancing in soft tissue Original Research Article Pages 285-293 4. A study of the metabolism of transplanted tumor in the lung by micro PET/CT in mice 5. Design parameters and the material coupling are decisive for the micromotion magnitude at the stem–neck interface of bi-modular hip implants(More)
Rupture of the abdominal aortic aneurysm (AAA) occurs when the local wall stress exceeds the local wall strength. Knowledge of AAA wall mechanics plays a fundamental role in the development and advancement of AAA rupture risk assessment tools. Therefore, the aim of this study is to evaluate the biaxial mechanical properties of AAA tissue. Multiple biaxial(More)
Currently, abdominal aortic aneurysms (AAAs), which are a permanent dilation of the aorta, are treated surgically when the maximum transverse diameter surpasses 5.5cm. AAA rupture occurs when the locally acting wall stress exceeds the locally acting wall strength. There is a need to review the current diameter-based criterion, and so it may be clinically(More)
Coronary artery disease can be treated by implanting a stent into the blocked region of an artery, thus enabling blood perfusion to distal vessels. Minimally invasive procedures of this nature often result in damage to the arterial tissue culminating in the re-blocking of the vessel. In an effort to alleviate this phenomenon, known as restenosis, drug(More)
INTRODUCTION A well-functioning arteriovenous fistula (AVF) is the best modality for vascular access in patients with end-stage renal disease (ESRD) requiring haemodialysis (HD). However, AVFs' main disadvantage is the high rate of maturation failure, with approximately one third (20%-50%) not maturing into useful access. This review examine the use of(More)
ABBREVIATIONS pulsatile1 = pulsatile flow case based on cycle-averaged inlet WSS = 12 dyn/cm 2 pulsatile2 = pulsatile flow case based on cycle-averaged inlet WSS = 15 dyn/cm 2 AV1 = Cycle-averaged flow, pulsatile1 case AV2 = Cycle-averaged flow, pulsatile2 case PK1 = Peak-systolic flow, pulsatile1 case PK2 = Peak-systolic flow, pulsatile2 case SS1 = Steady(More)