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PURPOSE Since little is known of the associations between bladder carcinoma and human papillomaviruses (HPVs), data on the role of HPV in bladder carcinogenesis are controversial. We attempted to clarify whether HPVs are present in bladder carcinomas. MATERIALS AND METHODS We examined 36 specimens of bladder carcinoma for HPV positivity by the polymerase(More)
OBJECTIVE To determine the safety and immunogenicity of childhood vaccines in children with perinatally acquired human immunodeficiency virus type 1 (HIV-1) infection. DESIGN Nonrandomized, prospective cohort study; 12-month follow-up period. SETTING Obstetric wards and outpatient pediatric clinics at two large hospitals in Kinshasa, Zaire. PATIENTS A(More)
Human papillomavirus (HPV) types 16 and 18 are most prevalent in cervical carcinomas and are also present in metastatic sites. Thirty-six patients with lymph node metastases were examined for the possible presence of HPV 16 and 18 DNA sequences in the primary tumors as well as in metastatic lymph nodes. Polymerase chain reaction (PCR) analysis revealed the(More)
Thirty-two cervical adenocarcinomas and adenosquamous carcinomas were examined to search for human papillomaviruses (HPVs) using the polymerase chain reaction system. Human papillomavirus type 16 (HPV16) and type 18 (HPV18) deoxyribonucleic acid was detected in 22% and 16% of these carcinomas, respectively. HPV16 was the most common type in both(More)
OBJECTIVES To assess the impact of the manual vacuum aspiration (MVA) technique on health care services and its acceptability to patients and staff. DESIGN Prospective descriptive survey. SETTING The university teaching hospital, Blantyre, Malawi. PARTICIPANTS All 456 patients who had MVA for treatment or investigation between 10 January and 9 April(More)
BACKGROUND Establishment of effective combination chemotherapy regimen for patients with an adenocarcinoma of the uterine cervix has been long-awaited because there has been no documentation concerning chemosensitivity of this tumor against conventional antitumor agents. METHODS To search for an effective combination regimen, 15 conventional antitumor(More)
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