- Publications
- Influence
Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications.
- M T Kasaian, Matthew J. Whitters, +12 authors M. J. Grusby
- Immunity
- 2002
IFNalpha/beta, IL-12, and IL-15 regulate NK cell activation and expansion, but signals triggering resolution of the NK response upon induction of adaptive immunity remain to be defined. We now report… (More)
- Matthew Ren Silver, Alexander Margulis, Nancy L. Wood, Samuel J. Goldman, M T Kasaian, Divya Chaudhary
- Inflammation Research
- 2009
ObjectiveMast cell and basophil activation contributes to inflammation, bronchoconstriction, and airway hyperresponsiveness in asthma. Because IL-33 expression is inflammation inducible, we… (More)
- M T Kasaian, Hideyuki Ikematsu, Paolo Casali
- Journal of immunology
- 1992
The production of "natural" autoantibodies or antibodies, i.e., Ig that bind a variety of self- and/or exogenous Ag and arise independently of known immunization, is though to be a feature of CD5+ B… (More)
- Gail M Gauvreau, Louis-Philippe Boulet, +16 authors Paul M O'Byrne
- American journal of respiratory and critical care…
- 2011
RATIONALE
Extensive evidence in animal models supports a role for IL-13 in the pathobiology of asthma. IMA-638 and IMA-026 are fully humanized IgG(1) antibodies that bind to different epitopes and… (More)
- Douglas C. Harnish, Leo M. Albert, +4 authors James C. Keith
- American journal of physiology. Gastrointestinal…
- 2004
A well-established model of bowel inflammation is the HLA-B27 transgenic rat that exhibits a spontaneous disease phenotype resulting in chronic diarrhea caused by immune cell activation. Estrogens… (More)
- Nancy Wood, Matthew J. Whitters, +10 authors M. J. Grusby
- The Journal of experimental medicine
- 2003
Interleukin (IL)-13 has recently been shown to play important and unique roles in asthma, parasite immunity, and tumor recurrence. At least two distinct receptor components, IL-4 receptor (R)alpha… (More)
- Nancy Wood, Karen Bourque, +4 authors M T Kasaian
- Cellular immunology
- 2004
In human atopic disease, IgE sensitizes the allergic response, while IgG4 is protective. Because IL-4 and IL-13 trigger switch recombination to both IgE and IgG4, additional agents must regulate the… (More)
- Susan C Fish, Debra D. Donaldson, Samuel J. Goldman, Cara M. M. Williams, M T Kasaian
- Journal of immunology
- 2005
IL-4 and IL-13 are potent cytokines that drive production of IgE, which is critical to the development of atopic disease. In this study, we directly compared IgE generation and IgE-dependent mast… (More)
- M T Kasaian, Douglas K. Miller
- Biochemical pharmacology
- 2008
Interleukin-13 (IL-13) is a critical mediator of asthma pathology. On B cells, monocytes, epithelial cells, and smooth muscle cells, IL-13 acts through the IL-13Ralpha1/IL-4Ralpha complex to directly… (More)
- M T Kasaian, Kimberly A. Leite-Morris, Christine A. Biron
- Journal of immunology
- 1991
The murine immune response to lymphocytic choriomeningitis virus (LCMV) infection involves the activation of CD8+, class I MHC-restricted and virus-specific CTL. At times coinciding with CTL… (More)