M T Corcuera Pindado

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Zidovudine (azidothymidine, AZT), a drug used in acquired immune deficiency syndrome (AIDS), blocks reverse transcriptase and therefore inhibits human immunodeficiency virus (HIV) replication. We carried out an ultrastructural and histoenzymatic study in rat cardiac muscle. Groups of animals (3 rats per group) were given drinking water with or without AZT(More)
OBJECTIVE Portal hypertension as an inducer of intestinal inflammatory response would cause epithelial and splanchnic vascular remodeling in the long-term. This experimental study was carried out to verify this hypothesis. METHOD Structural alterations characteristic of intestinal epithelial and mesenteric vascular remodeling, the density of goblet cells(More)
OBJECTIVE Recently has been described alterations in different organs of HIV + patients treated with zidovudine (AZT), as secondary effect from drug administration. METHOD We have developed and experimental rat model, in which the rats were administered AZT in drinking water and we have analysed the activity of enzyme isocitrate DH, of Krebs cycle, in(More)
Today, there are a great number of investigations about alcoholism. The effects of alcohol had been studied in Medicine, Psychology, Biology, Biochemistry, Physiology or Pharmacology. Many investigations are carried out with humans, however, in most experiments is necessary to use animal models. Many experimental models of alcoholism in animals are usually(More)
Primary Effusion Lymphoma is an unusual entity and it has been described as a subset associated with human herpes virus 8 infection in homosexual males with AIDS. Its inclusion as a new entity in the Revised European-American Lymphoma Classification has been recommended. The case in which it is presented is a 47-year-old man, diagnosed with AIDS two years(More)
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